Braddy Aaron, Mogal Rahul Janardan, Maddox Anthony John, Barlow Andrew Bryan Timothy
National Heart and Lung Institute, Imperial College London, London, UK.
Department of Respiratory Medicine, West Hertfordshire Hospitals NHS Trust, Watford, UK.
Eur J Case Rep Intern Med. 2020 Jun 1;7(8):001711. doi: 10.12890/2020_001711. eCollection 2020.
We describe the novel case of a patient presenting with pulmonary mucosa-associated lymphoid tissue lymphoma (pMALToma) synchronous with metastatic prostate adenocarcinoma.
We report the clinical, laboratory, radiological and histological findings of the above patient.
While the patient's metastatic prostate adenocarcinoma responded well to chemo-radio-hormonal therapy, a persistent area of lung consolidation was noted and further investigated, leading to the diagnosis of concurrent pMALToma.
It is important to pursue further investigation when there appears to be persistent change or altered disease response in malignancy if there is evidence for disease response elsewhere, as there may be two synchronous primary cancers.
This is a novel case where pulmonary mucosa-associated lymphoid tissue lymphoma (pMALToma), a rare disease entity, presented synchronously and asymptomatically in a patient with metastatic prostate adenocarcinoma.From an instructive errors perspective, it is important to consider synchronous primary malignancy and pursue further investigations, as appropriate, when there appears to be persistent change or altered disease response if there is evidence for disease response elsewhere.
我们描述了一例患有肺黏膜相关淋巴组织淋巴瘤（pMALToma）并同时伴有转移性前列腺腺癌的患者的新病例。
我们报告了上述患者的临床、实验室、影像学和组织学检查结果。
虽然患者的转移性前列腺腺癌对放化疗和激素治疗反应良好，但肺部持续存在实变区域，对此进行了进一步检查，最终诊断为同时存在pMALToma。
如果在其他部位有疾病缓解的证据，但在恶性肿瘤中出现持续变化或疾病反应改变时，进行进一步检查很重要，因为可能存在两种同步原发癌。
这是一例罕见的肺黏膜相关淋巴组织淋巴瘤（pMALToma）与转移性前列腺腺癌患者同步且无症状出现的新病例。从有指导意义的错误角度来看，当在其他部位有疾病缓解证据但出现持续变化或疾病反应改变时，考虑同步原发性恶性肿瘤并进行适当的进一步检查很重要。
