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免疫功能低下的器官移植受者中的2019冠状病毒病:一例报告及文献综述

Coronavirus Disease 2019 in Immunocompromised Organ Transplant Recipients: A Case Report and Review of the Literature.

作者信息

Taha Muhanad, Sharma Aditi, Taha Mazen, Samavati Lobelia

机构信息

Department of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, Michigan, United States.

Department of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, Michigan, United States.

出版信息

Transplant Proc. 2020 Nov;52(9):2698-2702. doi: 10.1016/j.transproceed.2020.07.014. Epub 2020 Jul 30.

Abstract

Coronavirus disease 2019 (COVID-19) is an ongoing pandemic caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2. Our understanding of this new disease continues to grow. The impact of the disease on immunocompromised transplant recipients is largely unknown. We present a case of a solid organ transplant recipient on immunosuppressive therapy who successfully recovered from COVID-19 infection. We also review 10 similar cases found in the literature and describe the clinical course and management, including immunosuppressive therapy.

摘要

2019冠状病毒病(COVID-19)是由一种名为严重急性呼吸综合征冠状病毒2的新型冠状病毒引起的正在流行的疾病。我们对这种新疾病的认识在不断加深。该疾病对免疫功能低下的移植受者的影响在很大程度上尚不清楚。我们报告一例接受免疫抑制治疗的实体器官移植受者成功从COVID-19感染中康复的病例。我们还回顾了文献中发现的10例类似病例,并描述了临床病程及管理,包括免疫抑制治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04af/7392038/c08f7a044fc5/gr1_lrg.jpg

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