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Chemical screening identifies ROCK1 as a regulator of migrasome formation.

作者信息

Lu Puzhong, Liu Rui, Lu Di, Xu Yue, Yang Xueyi, Jiang Zheng, Yang Chun, Yu Li, Lei Xiaoguang, Chen Yang

机构信息

The State Key Laboratory of Membrane Biology, Tsinghua University-Peking University Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, 100084 Beijing, China.

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking-Tsinghua Center for Life Science, Peking University, 100871 Beijing, China.

出版信息

Cell Discov. 2020 Aug 4;6(1):51. doi: 10.1038/s41421-020-0179-6. eCollection 2020.

DOI:10.1038/s41421-020-0179-6
PMID:32802402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7400516/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/7400516/7b7ce5128b65/41421_2020_179_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/7400516/7b7ce5128b65/41421_2020_179_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/7400516/7b7ce5128b65/41421_2020_179_Fig1_HTML.jpg

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本文引用的文献

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2
Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation.迁移体在斑马鱼原肠胚形成过程中为器官形态发生提供区域线索。
Nat Cell Biol. 2019 Aug;21(8):966-977. doi: 10.1038/s41556-019-0358-6. Epub 2019 Aug 1.
3
Identification of markers for migrasome detection.用于迁移体检测的标志物鉴定。
肾细胞癌中与迁移体相关的长链非编码RNA的风险和预后模型构建
Sci Rep. 2025 Jul 23;15(1):26760. doi: 10.1038/s41598-025-10630-w.
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A decade of discovery: tracing the footmarks of migrasomes, unveiling the footprints of cells.十年探索：追踪迁移小体的踪迹，揭示细胞的足迹。
Sci China Life Sci. 2025 Jul 18. doi: 10.1007/s11427-024-2883-2.
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Migrasomes: key players in immune regulation and promising medical applications.迁移小体：免疫调节的关键参与者及有前景的医学应用
Front Immunol. 2025 May 15;16:1592314. doi: 10.3389/fimmu.2025.1592314. eCollection 2025.
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Neutrophils secrete exosome-associated DNA to resolve sterile acute inflammation.中性粒细胞分泌外泌体相关DNA以消退无菌性急性炎症。
Nat Cell Biol. 2025 May 22. doi: 10.1038/s41556-025-01671-4.
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Migrasomes as intercellular messengers: potential in the pathological mechanism, diagnosis and treatment of clinical diseases.迁移小体作为细胞间信使：在临床疾病病理机制、诊断和治疗中的潜力
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