Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Social Medicine, School of Public Health, Dezful University of Medical Sciences, Dezful, Iran.
J Prev Med Hyg. 2020 Jul 4;61(2):E259-E289. doi: 10.15167/2421-4248/jpmh2020.61.2.1244. eCollection 2020 Jun.
Liver cancer (LC) is ranked seventh common cancer in terms of the incidence; and the fourth in terms of the mortality of cancer in the world. The aim of this study was to investigate the international distribution of the incidence and mortality of LC in 2018 based on various socio-economic and political divisions in the world.
This study was conducted through the use of the incidence and mortality cancer data from GLOBOCAN Project in 2018. The Age-Standardized Incidence Rate (ASIR) and Age Standardized Mortality Rate (ASMR) of LC were expressed per 100,000 people. In the current report, we used Pearson correlation method to assess the correlation between ASIR and ASMR. Statistical significance was considered to be P < 0.05.
The highest ASIR and ASMR of LC occurred in Asia (ASIR = 11.4 and ASMR = 10.5), and Western Pacific Region of the World Health Organization (ASIR = 17.4 and ASMR = 15.8), and those regions with income level equal to upper middle income (ASIR = 13.4 and ASMR = 6.6). Furthermore, the lowest ASIR and ASMR of LC occurred in in Latin America and Caribbean (ASIR = 5) and Europe (ASMR = 4.4), the South-East Asia region (ASIR = 4.5 and ASMR = 4.3), and regions with Low middle income (ASIR = 5.7) and regions with high income (ASMR = 2.7).
LC is one of the most important cancer forms in the world in terms of incidence and mortality. It is important to prevent exposure to known risk factors for LC by increasing the level of knowledge and attitudes of the community and prevent of morbidity and mortality of the population with early diagnosis and treatment of patients.
肝癌（LC）是全球发病率排名第七的常见癌症，死亡率排名第四。本研究旨在基于全球各种社会经济和政治划分，调查 2018 年 LC 的发病率和死亡率的国际分布。
本研究通过使用 GLOBOCAN 项目 2018 年的癌症发病率和死亡率数据进行。LC 的年龄标准化发病率（ASIR）和年龄标准化死亡率（ASMR）表示为每 10 万人中的人数。在本报告中，我们使用皮尔逊相关方法评估 ASIR 和 ASMR 之间的相关性。统计显著性被认为是 P < 0.05。
LC 的最高 ASIR 和 ASMR 发生在亚洲（ASIR = 11.4 和 ASMR = 10.5）和世界卫生组织西太平洋地区（ASIR = 17.4 和 ASMR = 15.8），以及收入水平相当于中上收入的地区（ASIR = 13.4 和 ASMR = 6.6）。此外，LC 的最低 ASIR 和 ASMR 发生在拉丁美洲和加勒比地区（ASIR = 5）和欧洲（ASMR = 4.4）、东南亚地区（ASIR = 4.5 和 ASMR = 4.3）以及中低收入地区（ASIR = 5.7）和高收入地区（ASMR = 2.7）。
LC 是全球发病率和死亡率最高的癌症之一。通过提高社区的知识水平和态度，预防已知的 LC 危险因素的暴露，以及通过早期诊断和治疗患者来预防发病率和死亡率，对于预防 LC 非常重要。
