Students' Scientific Center, Tehran University of Medical Sciences, Tehran, Iran.
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Adv Nutr. 2021 Feb 1;12(1):179-196. doi: 10.1093/advances/nmaa090.
Subcutaneous abdominal adipose tissue (SAT), is the largest fat depot and major provider of free fatty acids to the liver. Abdominal fat is indirectly (via increased levels of low-grade inflammation) correlated with many of the adverse health effects of obesity. Although exercise is one of the most prominent components of obesity management, its effects on SAT are still unclear. The aim of this study was to investigate the independent effects of aerobic training (AT) and resistance training (RT) modalities and combined exercise modalities on SAT in adults. PubMed, SCOPUS, and Google Scholar were searched to find relevant publications up to November 2018. The effect sizes were represented as weighted mean difference (WMD) and 95% CIs. Between-study heterogeneity was examined using the I2 test. Overall, 43 identified trials that enrolled 3552 subjects (2684 women) were included. After removal of outliers, combining effect sizes indicated a significant effect of AT (WMD: -13.05 cm2; 95% CI: -18.52, -7.57; P < 0.001), RT (WMD: -5.39 cm2; 95% CI: -9.66, -1.12; P = 0.01), and combined exercise training (CExT; WMD: -28.82 cm2; 95% CI: -30.83, -26.81; P < 0.001) on SAT relative to control groups. Pooled effect sizes demonstrated a significant effect of AT on SAT compared with a CExT group (WMD: 11.07 cm2; 95% CI: 1.81, 20.33; P = 0.01). However, when comparing the AT and RT groups, no significant difference was seen in SAT (WMD: -0.73 cm2; 95% CI: -4.50, 3.04; P = 0.70). Meta-analysis of relevant trials indicated that AT, RT, and CExT lead to SAT reduction. Aerobic exercise was shown to produce greater efficacy in decreasing SAT.
皮下腹部脂肪组织（SAT）是最大的脂肪库，也是肝脏游离脂肪酸的主要供应者。腹部脂肪通过（通过增加低度炎症水平）与肥胖的许多不良健康影响间接相关。尽管运动是肥胖管理的最突出组成部分之一，但它对 SAT 的影响仍不清楚。本研究旨在探讨有氧运动（AT）和抗阻运动（RT）以及联合运动方式对成人 SAT 的独立影响。在 PubMed、SCOPUS 和 Google Scholar 上进行了搜索，以查找截至 2018 年 11 月的相关出版物。效应大小表示为加权均数差（WMD）和 95%置信区间（CI）。使用 I2 检验检查研究间的异质性。总体而言，纳入了 43 项试验，共纳入 3552 名受试者（2684 名女性）。去除离群值后，合并效应大小表明 AT（WMD：-13.05cm2；95%CI：-18.52，-7.57；P<0.001）、RT（WMD：-5.39cm2；95%CI：-9.66，-1.12；P=0.01）和联合运动训练（CExT；WMD：-28.82cm2；95%CI：-30.83，-26.81；P<0.001）对 SAT 的影响明显优于对照组。汇总效应大小表明，与 CExT 组相比，AT 对 SAT 的影响更为显著（WMD：11.07cm2；95%CI：1.81，20.33；P=0.01）。然而，当比较 AT 和 RT 组时，SAT 无显著差异（WMD：-0.73cm2；95%CI：-4.50，3.04；P=0.70）。对相关试验的荟萃分析表明，AT、RT 和 CExT 可导致 SAT 减少。有氧运动在减少 SAT 方面显示出更大的疗效。
