Department of Surgery, North Florida/South Georgia Veterans Health System, Gainesville, Florida.
Department of Surgery, North Florida/South Georgia Veterans Health System, Gainesville, Florida; Department of Surgery, University of Florida College of Medicine, Gainesville, Florida.
J Surg Res. 2020 Dec;256:570-576. doi: 10.1016/j.jss.2020.07.033. Epub 2020 Aug 14.
Hiatal hernia recurrence after hiatal hernia repair (HHR) is often underdiagnosed and underreported but may present with recurrent gastroesophageal reflux disease (GERD) symptoms. Because of their availability, proton pump inhibitor (PPI) use is common and may mask patients who would benefit from revisional surgery, which has been shown to improve symptoms and quality of life.
A retrospective analysis was performed to evaluate recurrence patterns of patients who underwent HHR, specifically for the indication of GERD, from 2007 to 2015 at a single Veterans Administration Medical Center. Clinicopathologic parameters were reviewed for association with hiatal hernia recurrence, including postoperative PPI use.
Sixty-four patients were identified with a median follow-up time of 57.8 mo. Thirty-eight patients developed an anatomic recurrence, which did not demonstrate any associated factors on univariate analysis. Seventy percent of patients remained or were restarted on PPI after their initial surgery. For patients with a documented recurrence, the median time to start a PPI was 224 d, but the time to identify recurrence on imaging or endoscopy was 712.5 d. Eleven (39.3%) patients had a reintervention for anatomic recurrence, of which all had developed recurrent symptoms of GERD.
Most patients who developed recurrent hiatal hernia were restarted on PPI without workup for their symptoms. The time of initiation of PPI was much earlier than the time of identification of a recurrent hiatal hernia. The use of PPIs in patients whom have undergone HHR may delay proper workup to identify recurrent hiatal hernia amenable to surgical repair and should be reserved until patients develop recurrent symptoms and have at least begun a diagnostic workup to rule out an anatomic cause for the recurrent symptoms.
食管裂孔疝修补术后食管裂孔疝复发(HHR)常被漏诊和低估,但可能表现为复发性胃食管反流病(GERD)症状。由于质子泵抑制剂(PPI)的可用性,其使用很常见,可能会掩盖需要接受修正手术的患者,因为手术已被证明可以改善症状和生活质量。
对 2007 年至 2015 年期间在一家退伍军人管理局医疗中心因 GERD 指征接受 HHR 的患者的复发模式进行回顾性分析。对临床病理参数进行了回顾分析,以评估其与食管裂孔疝复发的相关性,包括术后 PPI 的使用。
确定了 64 例患者,中位随访时间为 57.8 个月。38 例患者出现解剖学复发,但单变量分析未显示任何相关因素。70%的患者在初次手术后仍继续或重新开始使用 PPI。对于有记录的复发患者,开始使用 PPI 的中位时间为 224 天,但在影像学或内镜检查中识别复发的时间为 712.5 天。11(39.3%)例患者因解剖学复发而再次接受干预,所有患者均出现复发性 GERD 症状。
大多数出现复发性食管裂孔疝的患者在没有对其症状进行检查的情况下重新开始使用 PPI。开始使用 PPI 的时间早于识别复发性食管裂孔疝的时间。在接受 HHR 的患者中使用 PPI 可能会延迟对复发性食管裂孔疝进行适当检查,而这种疝适合手术修复,因此 PPI 应保留给出现复发性症状且至少已开始诊断性检查以排除复发性症状的解剖原因的患者。