Kniep I, Lutter M, Ron A, Edler C, Püschel K, Ittrich H, Heller M, Heinemann A
Institut für Rechtsmedizin, Universitätsklinikum Hamburg-Eppendorf, Butenfeld 34, 22529, Hamburg, Deutschland.
Klinik und Poliklinik für Diagnostische und Interventionelle Radiologie und Nuklearmedizin, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
Radiologe. 2020 Oct;60(10):927-933. doi: 10.1007/s00117-020-00733-y.
CLINICAL/METHODOLOGICAL ISSUE: COVID-19 is a new viral disease that is associated with inflammatory pulmonary changes which can be detected in computed tomography (CT). So far postmortem CT (PMCT) has not been used as a screening instrument for the evaluation of deaths with and without autopsy. In this respect, its validity has to be proved in comparison to clinical-radiological experiences.
Postmortem CT METHODICAL INNOVATIONS: So far, PMCT can be regarded as a methodological innovation that has not yet been sufficiently evaluated for pneumonia.
CT in clinical routine has a high sensitivity for pneumonia. However, to what extent postmortem artifacts are relevant to PMCT still has to be determined.
There is still no standard procedure for the postmortem radiological diagnosis of COVID-19 disease. Despite postmortem artifacts, PMCT can provide valuable information about the presence of pneumonia with interstitial character, especially without autopsy.
PMCT is particularly useful in the assessment of suspected cases of COVID-19 pneumonia for morphological assessment in the context of monitoring deaths in the current pandemic situation.
临床/方法学问题：新型冠状病毒肺炎（COVID-19）是一种新型病毒性疾病，与可通过计算机断层扫描（CT）检测到的肺部炎症性改变相关。迄今为止，尸检CT（PMCT）尚未用作评估有无尸检的死亡情况的筛查工具。在这方面，必须将其有效性与临床放射学经验进行比较来加以证明。
尸检CT 方法学创新：到目前为止，PMCT可被视为一种方法学创新，尚未针对肺炎进行充分评估。
临床常规中的CT对肺炎具有高敏感性。然而，尸检伪影与PMCT的相关程度仍有待确定。
对于COVID-19疾病的尸检放射学诊断，目前仍没有标准程序。尽管存在尸检伪影，但PMCT可提供有关间质性肺炎存在的有价值信息，尤其是在没有尸检的情况下。
在当前大流行情况下监测死亡病例时，PMCT对于评估疑似COVID-19肺炎病例进行形态学评估特别有用。
