• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过具有金刚烷基功能化卟啉和环糊精二聚体的超分子光敏剂增强光动力疗法。

Enhanced photodynamic therapy through supramolecular photosensitizers with an adamantyl-functionalized porphyrin and a cyclodextrin dimer.

机构信息

Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.

出版信息

Chem Commun (Camb). 2020 Sep 25;56(75):11134-11137. doi: 10.1039/d0cc03574b. Epub 2020 Aug 20.

DOI:10.1039/d0cc03574b
PMID:32815939
Abstract

A supramolecular photosensitizer was constructed using a tetra-adamantane-functionalized porphyrin and a dimer of permethyl-β-cyclodextrin through host-guest interaction and self-assembly. The porphyrin/cyclodextrin alternating structure of supramolecular photosensitizers not only enhances the water solubility of the photosensitizers, but also effectively inhibits the aggregation-induced quenching of porphyrin photosensitizers.

摘要

一种超分子光敏剂是通过主客体相互作用和自组装,使用四金刚烷功能化卟啉和二聚体的甲基-β-环糊精构建的。超分子光敏剂的卟啉/环糊精交替结构不仅提高了光敏剂的水溶性,而且有效抑制了卟啉光敏剂的聚集诱导猝灭。

相似文献

1
Enhanced photodynamic therapy through supramolecular photosensitizers with an adamantyl-functionalized porphyrin and a cyclodextrin dimer.通过具有金刚烷基功能化卟啉和环糊精二聚体的超分子光敏剂增强光动力疗法。
Chem Commun (Camb). 2020 Sep 25;56(75):11134-11137. doi: 10.1039/d0cc03574b. Epub 2020 Aug 20.
2
Linear Alternating Supramolecular Photosensitizer for Enhanced Photodynamic Therapy.线性交替超分子光敏剂增强光动力疗法。
ACS Appl Mater Interfaces. 2020 Jul 22;12(29):32352-32359. doi: 10.1021/acsami.0c07333. Epub 2020 Jul 9.
3
Design and synthesis of zinc protoporphyrin IX-adamantane/cyclodextrin/cellulose nanocrystals complexes for anticancer photodynamic therapy.设计并合成锌原卟啉 IX-金刚烷/环糊精/纤维素纳米晶复合物用于抗癌光动力治疗。
Bioorg Med Chem Lett. 2021 Jun 1;41:128024. doi: 10.1016/j.bmcl.2021.128024. Epub 2021 Apr 9.
4
Targeted Delivery and Site-Specific Activation of β-Cyclodextrin-Conjugated Photosensitizers for Photodynamic Therapy through a Supramolecular Bio-orthogonal Approach.通过超分子生物正交方法靶向递送至β-环糊精缀合的光动力治疗光敏剂及其定点激活。
J Med Chem. 2021 Oct 28;64(20):15461-15476. doi: 10.1021/acs.jmedchem.1c01505. Epub 2021 Oct 18.
5
Mitochondria-targeting and ROS-sensitive smart nanoscale supramolecular organic framework for combinational amplified photodynamic therapy and chemotherapy.线粒体靶向和 ROS 敏感的智能纳米超分子有机框架用于联合放大光动力疗法和化学疗法。
Acta Biomater. 2021 Aug;130:447-459. doi: 10.1016/j.actbio.2021.05.048. Epub 2021 May 31.
6
Efficient photosensitization by a chlorin-polyoxometalate supramolecular complex.高效的卟啉-多金属氧酸盐超分子复合物敏化作用。
Inorg Chem. 2014 Jan 6;53(1):3-5. doi: 10.1021/ic401729k. Epub 2013 Dec 9.
7
Pillar[5]arene-Based Switched Supramolecular Photosensitizer for Self-Amplified and pH-Activated Photodynamic Therapy.基于多足芳烃的切换型超分子光引发剂用于自增强和 pH 激活的光动力疗法。
ACS Appl Mater Interfaces. 2020 Sep 16;12(37):41038-41046. doi: 10.1021/acsami.0c10372. Epub 2020 Sep 4.
8
Improved water solubility and photodynamic activity of hydroxy-modified porphyrins by complexation with cyclodextrin.通过与环糊精络合来提高羟基修饰卟啉的水溶性和光动力活性。
Org Biomol Chem. 2020 Sep 14;18(34):6702-6709. doi: 10.1039/d0ob01379j. Epub 2020 Aug 21.
9
Self-Assembly of Porphyrin-Containing Metalla-Assemblies and Cancer Photodynamic Therapy.卟啉金属组装体的自组装和癌症光动力疗法。
Inorg Chem. 2020 Jun 1;59(11):7380-7388. doi: 10.1021/acs.inorgchem.9b02775. Epub 2020 Jan 21.
10
Synthesis, Photophysical Properties and Application of New Porphyrin Derivatives for Use in Photodynamic Therapy and Cell Imaging.用于光动力疗法和细胞成像的新型卟啉衍生物的合成、光物理性质及应用
J Fluoresc. 2018 Jul;28(4):871-882. doi: 10.1007/s10895-018-2264-x. Epub 2018 Jul 16.

引用本文的文献

1
Applications of supramolecular assemblies in drug delivery and photodynamic therapy.超分子组装体在药物递送和光动力疗法中的应用。
RSC Med Chem. 2023 Oct 5;14(12):2438-2458. doi: 10.1039/d3md00396e. eCollection 2023 Dec 13.
2
Cyclodextrin-Based Nanoplatforms for Tumor Phototherapy: An Update.基于环糊精的肿瘤光疗纳米平台:最新进展
Pharmaceutics. 2022 Jun 29;14(7):1375. doi: 10.3390/pharmaceutics14071375.