Ghani Muhammad U, Li Yuhua, Wu Xizeng, Liu Hong
Advanced Medical Imaging Center and School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA.
Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, 35249, USA.
Nucl Instrum Methods Phys Res A. 2019 Sep 21;939:83-88. doi: 10.1016/j.nima.2019.05.054. Epub 2019 May 23.
The recent advancements in the photon counting detection have created a significant growing research interest in the x-ray imaging. It is essential to objectively understand the image quality parameters of a photon counting detector before developing imaging applications. In this work, we have assessed the imaging quality of a cadmium telluride (CdTe) based PCD in projection imaging mode. The detector is 70.4 mm × 6.6 mm dimensions. The detector has a pixel array of 64×4 with a pixel pitch of 1.1 mm×1.65 mm. With each pixel having 4 channels in its corresponding ASIC, this PCD can create three bin images from a single projection. With a microfocus x-ray source, the imaging quality in each bin image was measured in terms of the spatial resolution, noise, and contrast to noise ratio (CNR). We used 70 kV, 50μA, 10 s (0.5mAs) with 0.5mm thick aluminum (Al) filter for the acquisition of each image. The MTF curves indicated that the spatial resolution for the bin-1, bin-2, and bin-3 was almost identical. The NNPS curves indicated that the noise in bin 1 and bin 2 images was almost the same for all frequencies while bin 3 image had relatively less noise. The CNR analyses showed that the bin-1 image had the highest CNR. As the flux was increased from 0.5 to 1 mAs, the number of detected counts also increased that resulted in the CNR increase. Beyond this flux, the pulse pileup occurred due to which multiple counts were read as single that resulted in few detected counts and lower CNR. The knowledge of the spatial resolution, noise, and CNR in terms of energy binning allows the determination and optimization of imaging techniques necessary for various applications.
光子计数检测技术的最新进展引发了对X射线成像的大量研究兴趣。在开发成像应用之前,客观了解光子计数探测器的图像质量参数至关重要。在这项工作中,我们评估了基于碲化镉(CdTe)的光子计数探测器在投影成像模式下的成像质量。该探测器尺寸为70.4毫米×6.6毫米。探测器具有64×4的像素阵列,像素间距为1.1毫米×1.65毫米。每个像素在其相应的专用集成电路中有4个通道,这种光子计数探测器可以从单个投影中创建三个能谱图像。使用微焦点X射线源,根据空间分辨率、噪声和对比度噪声比(CNR)测量每个能谱图像的成像质量。我们使用70 kV、50μA、10秒(0.5 mAs)以及0.5毫米厚的铝(Al)滤光片来采集每张图像。调制传递函数(MTF)曲线表明,能谱1、能谱2和能谱3的空间分辨率几乎相同。噪声功率谱(NNPS)曲线表明,能谱1和能谱2图像在所有频率下的噪声几乎相同,而能谱3图像的噪声相对较小。对比度噪声比(CNR)分析表明,能谱1图像的CNR最高。随着通量从0.5 mAs增加到1 mAs,检测到的计数数量也增加,导致CNR增加。超过这个通量后,会发生脉冲堆积,由于多个计数被读取为单个计数,导致检测到的计数减少且CNR降低。关于能量分箱的空间分辨率、噪声和CNR的知识有助于确定和优化各种应用所需的成像技术。