Leng Shuai, Yu Zhicong, Halaweish Ahmed, Kappler Steffen, Hahn Katharina, Henning Andre, Li Zhoubo, Lane John, Levin David L, Jorgensen Steven, Ritman Erik, McCollough Cynthia
Mayo Clinic , Department of Radiology, 200 First Street Southwest, Rochester, Minnesota 55905, United States.
Siemens Healthcare , Malvern, Pennsylvania 19355, United States.
J Med Imaging (Bellingham). 2016 Oct;3(4):043504. doi: 10.1117/1.JMI.3.4.043504. Epub 2016 Dec 22.
An ultrahigh-resolution (UHR) data collection mode was enabled on a whole-body, research photon counting detector (PCD) computed tomography system. In this mode, 64 rows of [Formula: see text] detector pixels were used, which corresponded to a pixel size of [Formula: see text] at the isocenter. Spatial resolution and image noise were quantitatively assessed for the UHR PCD scan mode, as well as for a commercially available UHR scan mode that uses an energy-integrating detector (EID) and a set of comb filters to decrease the effective detector size. Images of an anthropomorphic lung phantom, cadaveric swine lung, swine heart specimen, and cadaveric human temporal bone were qualitatively assessed. Nearly equivalent spatial resolution was demonstrated by the modulation transfer function measurements: 15.3 and [Formula: see text] spatial frequencies were achieved at 10% and 2% modulation, respectively, for the PCD system and 14.2 and [Formula: see text] for the EID system. Noise was 29% lower in the PCD UHR images compared to the EID UHR images, representing a potential dose savings of 50% for equivalent image noise. PCD UHR images from the anthropomorphic phantom and cadaveric specimens showed clear delineation of small structures.
在一台全身研究型光子计数探测器（PCD）计算机断层扫描系统上启用了超高分辨率（UHR）数据采集模式。在此模式下，使用了64排[公式：见原文]探测器像素，在等中心处对应像素尺寸为[公式：见原文]。对UHR PCD扫描模式以及一种市售的UHR扫描模式进行了空间分辨率和图像噪声的定量评估，后者使用能量积分探测器（EID）和一组梳状滤波器来减小有效探测器尺寸。对一个仿真人体肺部模型、猪尸体肺部、猪心脏标本和人体尸体颞骨的图像进行了定性评估。调制传递函数测量显示出几乎等效的空间分辨率：PCD系统在10%调制和2%调制时分别达到15.3和[公式：见原文]的空间频率，EID系统为14.2和[公式：见原文]。与EID UHR图像相比，PCD UHR图像中的噪声低29%，这意味着对于等效图像噪声而言，潜在的剂量节省为50%。来自仿真人体模型和尸体标本的PCD UHR图像清晰地显示出小结构。
