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麻疹样皮疹:新型冠状病毒肺炎的一种罕见前驱症状

Morbilliform Rash: An Uncommon Herald of SARS-CoV-2.

作者信息

Kulkarni Radhika B, Lederman Yitzchok, Afiari Agura, Savage Jacqueline A, Jacob Jason

机构信息

Internal Medicine, University of Connecticut, Farmington, USA.

Internal Medicine, University of Connecticut School of Medicine, Hartford, USA.

出版信息

Cureus. 2020 Jul 21;12(7):e9321. doi: 10.7759/cureus.9321.

DOI:10.7759/cureus.9321
PMID:32850199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7444743/
Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus first detected in Wuhan, China in 2019 after an outbreak of flu-like illness. The disease came to be known as the coronavirus disease of 2019 (COVID-19). It has spread quickly, spanning many countries, and has become a global pandemic. As this is a novel virus, its varied manifestations and symptomatology are coming to light daily. Although most threatening to the respiratory system, this virus has the propensity to affect multiple organ systems quickly leading to multi-organ dysfunction. Many dermatologic manifestations have been reported with no clear pattern. Most data have been anecdotal.  Here we present a 78-year-old male who tested positive for SARS-CoV-2 with no usual symptoms that would alert one of the possibilities of COVID-19. He did, however, have a diffuse morbilliform rash most notable on the trunk and back. He went on to develop fever thereafter but did not develop any respiratory complications. The rash was short-lived and was treated with topical steroids and oral antihistamines. It is important to know and report new findings of novel diseases not only for diagnosis and treatment but also to place appropriate isolation precautions and containment. Rash may be the initial and sometimes the only manifestation of COVID-19.

摘要

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)是一种新型冠状病毒,2019年在中国武汉出现类似流感疾病的疫情后首次被发现。这种疾病后来被称为2019冠状病毒病(COVID-19)。它传播迅速,波及许多国家,已成为全球大流行疾病。由于这是一种新型病毒,其多样的表现和症状学每天都在被揭示。尽管对呼吸系统威胁最大,但这种病毒有迅速影响多个器官系统的倾向,导致多器官功能障碍。已经报告了许多皮肤表现,但没有明确的模式。大多数数据都是轶事性的。在此,我们介绍一名78岁男性,他SARS-CoV-2检测呈阳性,没有任何能让人警惕COVID-19可能性的常见症状。然而,他确实出现了弥漫性麻疹样皮疹,最明显的部位是躯干和背部。此后他继续发烧,但未出现任何呼吸道并发症。皮疹持续时间较短,使用外用类固醇和口服抗组胺药进行了治疗。了解和报告新型疾病的新发现很重要,这不仅有助于诊断和治疗,还能采取适当的隔离预防措施和控制措施。皮疹可能是COVID-19的初始表现,有时甚至是唯一表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526a/7444743/29943a33b02f/cureus-0012-00000009321-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526a/7444743/3b7b4df79888/cureus-0012-00000009321-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526a/7444743/29943a33b02f/cureus-0012-00000009321-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526a/7444743/3b7b4df79888/cureus-0012-00000009321-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526a/7444743/29943a33b02f/cureus-0012-00000009321-i02.jpg

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本文引用的文献

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