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人类微生物组描述的策略和进展以及培养组学的重要性。

Strategies and advancements in human microbiome description and the importance of culturomics.

机构信息

Department of Bioengineering and ChEM-H, Stanford University, Stanford, CA, 94305, USA.

出版信息

Microb Pathog. 2020 Dec;149:104460. doi: 10.1016/j.micpath.2020.104460. Epub 2020 Aug 25.

Abstract

The human microbiota gained a big interest among the scientific community with numerous studies being performed to better understand its role in health and diseases. Even with all the success achieved in studying the bacterial populations at the different body sites and its interaction among each other and with the host, some links remain missing and might have therapeutic benefits. In this review, we summarize the main means used for bacterial identification, human microbiota description and the role of culturomics in leading the way towards the development of new bacterio-therapeutic approaches.

摘要

人类微生物群在科学界引起了极大的兴趣,进行了大量的研究来更好地了解其在健康和疾病中的作用。尽管在研究不同身体部位的细菌种群及其相互作用以及与宿主的相互作用方面取得了巨大的成功,但仍有一些联系缺失,并且可能具有治疗益处。在这篇综述中,我们总结了用于细菌鉴定、人类微生物组描述以及培养组学在引领新的细菌治疗方法发展方面的主要手段。

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