School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, PR China.
Hua An Tang Biotech Group Co., Ltd, Guangzhou, PR China.
Nat Prod Res. 2021 Dec;35(24):5977-5980. doi: 10.1080/14786419.2020.1809401. Epub 2020 Aug 28.
essential oils (BBEOs) and essential oils (MSEOs) have exhibited outstanding antioxidant, anti-bacterial and anti-inflammatory activities. However, their anti-photoaging ability is still unclear. In this study, the chemical compositions of BBEOs and MSEOs are firstly determined by GC-MS analysis, and then their anti-photoaging is evaluated via an ultraviolet radiation (UV-B) induced mice skin-injury model. A total of 35 and 33 components are identified from BBEOs and MSEOs, and their dominant compositions are caryophyllene (18.54%) and borneol (18.33%) in BBEOs, and β-elemene (29.10%), γ-terpinene (17.01%) and (E)-β-ocymene (11.69%) in MSEOs. According to the skin injury model, the application of BBEOs and MSEOs to mice skin can effectively inhibit skin photoaging by down-regulating the expression of inflammatory factors including TNF-α, IL-6 and IL-10. Clearly, both essential oils reveal the potential as additives in cosmetics for anti-photoaging.
精油（BBEOs）和精油（MSEOs）表现出了出色的抗氧化、抗菌和抗炎活性。然而，它们的抗光老化能力尚不清楚。在本研究中，我们首先通过 GC-MS 分析确定了 BBEOs 和 MSEOs 的化学成分，然后通过紫外线辐射（UV-B）诱导的小鼠皮肤损伤模型评估了它们的抗光老化能力。从 BBEOs 和 MSEOs 中分别鉴定出了 35 种和 33 种成分，它们的主要成分分别是 BBEOs 中的石竹烯（18.54%）和龙脑（18.33%），以及 MSEOs 中的 β-榄香烯（29.10%）、γ-萜品烯（17.01%）和（E）-β-罗勒烯（11.69%）。根据皮肤损伤模型，将 BBEOs 和 MSEOs 应用于小鼠皮肤可以有效抑制皮肤光老化，下调 TNF-α、IL-6 和 IL-10 等炎症因子的表达。显然，这两种精油都具有作为化妆品抗光老化添加剂的潜力。
