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与 精油的化学成分及预防 UV-B 辐射诱导皮肤光老化

Chemical composition of and essential oils and prevention of UV-B radiation-induced skin photoaging.

机构信息

School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, PR China.

Hua An Tang Biotech Group Co., Ltd, Guangzhou, PR China.

出版信息

Nat Prod Res. 2021 Dec;35(24):5977-5980. doi: 10.1080/14786419.2020.1809401. Epub 2020 Aug 28.

Abstract

essential oils (BBEOs) and essential oils (MSEOs) have exhibited outstanding antioxidant, anti-bacterial and anti-inflammatory activities. However, their anti-photoaging ability is still unclear. In this study, the chemical compositions of BBEOs and MSEOs are firstly determined by GC-MS analysis, and then their anti-photoaging is evaluated via an ultraviolet radiation (UV-B) induced mice skin-injury model. A total of 35 and 33 components are identified from BBEOs and MSEOs, and their dominant compositions are caryophyllene (18.54%) and borneol (18.33%) in BBEOs, and β-elemene (29.10%), γ-terpinene (17.01%) and (E)-β-ocymene (11.69%) in MSEOs. According to the skin injury model, the application of BBEOs and MSEOs to mice skin can effectively inhibit skin photoaging by down-regulating the expression of inflammatory factors including TNF-α, IL-6 and IL-10. Clearly, both essential oils reveal the potential as additives in cosmetics for anti-photoaging.

摘要

精油(BBEOs)和精油(MSEOs)表现出了出色的抗氧化、抗菌和抗炎活性。然而,它们的抗光老化能力尚不清楚。在本研究中,我们首先通过 GC-MS 分析确定了 BBEOs 和 MSEOs 的化学成分,然后通过紫外线辐射(UV-B)诱导的小鼠皮肤损伤模型评估了它们的抗光老化能力。从 BBEOs 和 MSEOs 中分别鉴定出了 35 种和 33 种成分,它们的主要成分分别是 BBEOs 中的石竹烯(18.54%)和龙脑(18.33%),以及 MSEOs 中的 β-榄香烯(29.10%)、γ-萜品烯(17.01%)和(E)-β-罗勒烯(11.69%)。根据皮肤损伤模型,将 BBEOs 和 MSEOs 应用于小鼠皮肤可以有效抑制皮肤光老化,下调 TNF-α、IL-6 和 IL-10 等炎症因子的表达。显然,这两种精油都具有作为化妆品抗光老化添加剂的潜力。

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