免疫珠试验结果与精子穿透试验结果之间的相关性。

Correlations between results of the immunobead test and the sperm penetration assay.

作者信息

Gocial B, Corson S L, Batzer F R, Maislin G, Marmar J

机构信息

Department of Obstetrics and Gynecology, Philadelphia Fertility Institute, PA 19107-6096.

出版信息

Am J Reprod Immunol Microbiol. 1988 Jan;16(1):37-41. doi: 10.1111/j.1600-0897.1988.tb00174.x.

DOI:10.1111/j.1600-0897.1988.tb00174.x

PMID:3285709

Abstract

Immunobead testing (IBT) and human sperm-hamster egg penetration assay (SPA) were performed in 233 infertile men. Positive immunologic results were recorded in 31 (13.3%). Significant reduction in SPA scores was found in patients with IgG antisperm antibodies alone but not in patients with IgA alone or in combination with IgG. Normal SPA scores were seen in 56% of immunonegative patients (n = 113) vs. 32% of immunopositive patients (n = 10). Therefore, a normal SPA does not rule out the presence of significant levels of antisperm antibodies.

摘要

对233名不育男性进行了免疫珠试验（IBT）和人精子-仓鼠卵穿透试验（SPA）。31名（13.3%）患者免疫结果呈阳性。仅存在IgG抗精子抗体的患者SPA评分显著降低，但仅存在IgA或同时存在IgA和IgG的患者则未出现这种情况。免疫阴性患者（n = 113）中有56%的人SPA评分正常，而免疫阳性患者（n = 10）中这一比例为32%。因此，SPA评分正常并不能排除存在高水平抗精子抗体的可能性。