Department of Diagnostic Imaging, Oncological Radiotherapy, and Hematology - Diagnostic Imaging Area, Italy; Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy.
Department of Diagnostic Imaging, Oncological Radiotherapy, and Hematology - Diagnostic Imaging Area, Italy; Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy.
Eur J Radiol. 2020 Oct;131:109217. doi: 10.1016/j.ejrad.2020.109217. Epub 2020 Aug 17.
Due to its pandemic diffusion, SARS- CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection represents a global threat. Despite a multiorgan involvement has been described, pneumonia is the most common manifestation of COVID-19 (Coronavirus disease 2019) and it is associated with a high morbidity and a considerable mortality. Especially in the areas with high disease burden, chest imaging plays a crucial role to speed up the diagnostic process and to aid the patient management. The purpose of this comprehensive review is to understand the diagnostic capabilities and limitations of chest X-ray (CXR) and high-resolution computed tomography (HRCT) in defining the common imaging features of COVID-19 pneumonia and correlating them with the underlying pathogenic mechanisms. The evolution of lung abnormalities over time, the uncommon findings, the possible complications, and the main differential diagnosis occurring in the pandemic phase of SARS-CoV-2 infection are also discussed.
由于其大流行的传播,SARS-CoV-2(严重急性呼吸系统综合征冠状病毒 2)感染构成了全球威胁。尽管已经描述了多器官受累,但肺炎是 COVID-19(2019 年冠状病毒病)最常见的表现,并且与高发病率和相当高的死亡率相关。特别是在疾病负担高的地区,胸部影像学在加速诊断过程和辅助患者管理方面发挥着至关重要的作用。本综述的目的是了解胸部 X 线(CXR)和高分辨率计算机断层扫描(HRCT)在定义 COVID-19 肺炎常见影像学特征方面的诊断能力和局限性,并将其与潜在的发病机制相关联。还讨论了随着时间的推移肺异常的演变、不常见的发现、可能的并发症以及 SARS-CoV-2 感染大流行期间的主要鉴别诊断。