Fogarty Matthew J, Sieck Gary C
Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, 55905, USA.
Drug Discov Today Dis Models. 2019 Summer;29-30:43-52. doi: 10.1016/j.ddmod.2019.10.002. Epub 2019 Nov 27.
Breathing is achieved without thought despite being controlled by a complex neural network. The diaphragm is the predominant muscle responsible for force/pressure generation during breathing, but it is also involved in other non-ventilatory expulsive behaviors. This review considers alterations in diaphragm muscle fiber types and the neural control of the diaphragm across our lifespan and in various disease conditions.
呼吸尽管受复杂神经网络控制，但无需意识参与即可完成。膈肌是呼吸过程中负责产生力量/压力的主要肌肉，不过它也参与其他非通气性的排出行为。本综述探讨了膈肌肌纤维类型的变化以及在我们整个生命周期和各种疾病状态下膈肌的神经控制。
