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瑞典一所新建兽医学院大楼及教学医院的生物安全考量与风险降低策略

Biosafety considerations and risk reduction strategy for a new veterinary faculty building and teaching hospital in Sweden.

作者信息

Wierup Martin, Allard Bengtsson Ulrika, Vågsholm Ivar

机构信息

Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences.

Department of Microbiology, National Veterinary Institute (SVA).

出版信息

Infect Ecol Epidemiol. 2020 Jun 4;10(1):1761588. doi: 10.1080/20008686.2020.1761588.

DOI:10.1080/20008686.2020.1761588
PMID:32864050
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7448862/
Abstract

INTRODUCTION

This paper describes a hazard- and risk-based strategy and recommendations on relevant biosafety levels in facility design of a new veterinary faculty building including a veterinary medical teaching hospital. Both animal and human health were considered.

MATERIALS AND METHODS

Agents listed in the regulatory frameworks on animal and human health were identified as the main potential hazards. Suggestions on biosafety level and facility design were based on the official risk grouping of those agents, the associated risk management procedures, and biosafety experiences from previous faculty buildings.

RESULTS AND DISCUSSION

It was suggested that VHC should not be designed for work with agents requiring facilities at biosafety levels 3 and 4, and that actions in cases of accidental exposure to notifiable infections should follow the regulatory requirements. Facilities requiring biosafety level 2 were identified from risk scenarios and transmission routes.Experiences from the first five years of operation revealed good prevention of spread of infection from patients in isolation facilities and successful elimination of Salmonella and MRSA from the large animal clinic.

CONCLUSION

In order to avoid costly construction mistakes, an overall biosafety strategy should be formulated and used as guidance for architects and other relevant stakeholders designing facilities for the animal health sector. Regulatory requirements on infectious diseases must be complied with.

摘要

引言

本文描述了一种基于危害和风险的策略以及关于新建兽医学院建筑(包括兽医教学医院)设施设计中相关生物安全水平的建议。同时考虑了动物和人类健康。

材料与方法

动物和人类健康监管框架中列出的病原体被确定为主要潜在危害。关于生物安全水平和设施设计的建议基于这些病原体的官方风险分组、相关风险管理程序以及以往学院建筑的生物安全经验。

结果与讨论

建议兽医学院不应设计用于处理需要生物安全3级和4级设施的病原体,并且在意外接触应通报感染的情况下,行动应遵循监管要求。从风险场景和传播途径中确定了需要生物安全2级的设施。运营头五年的经验表明,隔离设施中很好地预防了患者感染的传播,并且在大型动物诊所成功消除了沙门氏菌和耐甲氧西林金黄色葡萄球菌。

结论

为避免代价高昂的建设错误,应制定全面的生物安全策略,并将其用作指导为动物健康领域设计设施的建筑师和其他相关利益相关者的指南。必须遵守关于传染病的监管要求。

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