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3-（三甲氧基甲硅烷基）丙基二甲基十八烷基氯化铵作为一种抗菌和抗病毒剂用于个人防护装备消毒的潜在用途。

Potential use of 3-(trimethoxysilyl)propyldimethyl octadecyl ammonium chloride as an antimicrobial and antiviral agent for the disinfection of personal protective equipment.

作者信息

Kim Yujin, Youn Hana, Kim Junbeom, Lee Daye, Go Seonghye, Park Ji-Eun, Lee Sunhak, Noh Jinyong, Nahm Sang-Soep

机构信息

College of Veterinary Medicine, Konkuk University, Seoul, Korea.

Konkuk Ctc Bio Animal Vaccine Co. Ltd., Seoul, Korea.

出版信息

Clin Exp Vaccine Res. 2020 Jul;9(2):174-178. doi: 10.7774/cevr.2020.9.2.174. Epub 2020 Jul 31.

DOI:10.7774/cevr.2020.9.2.174
PMID:32864375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7445321/
Abstract

Currently, no vaccine or established therapeutic agents are available for coronavirus disease 2019. The sharp increase in demand for personal protective equipment (PPE) necessitates an improvement in the protective efficacy of PPE. We evaluated the potential antimicrobial and antiviral effects of a surface-coating disinfectant (3-(trimethoxysilyl)propyldimethyl octadecyl ammonium chloride, Si-QAC) when applied onto PPE. Si-QAC-pre-coated PPE was artificially contaminated with either influenza virus or . The results showed significantly reduced influenza and titers in Si-QAC-coated PPE; these antimicrobial effects lasted 7 days. This suggests that this surface-coating disinfectant effectively reduces pathogen contamination of PPE, enabling their safe and long-term use.

摘要

目前，2019冠状病毒病尚无可用疫苗或既定治疗药物。个人防护装备（PPE）需求的急剧增加使得提高其防护效果成为必要。我们评估了一种表面涂层消毒剂（3-（三甲氧基甲硅烷基）丙基二甲基十八烷基氯化铵，Si-QAC）应用于PPE时的潜在抗菌和抗病毒效果。Si-QAC预涂覆的PPE被人为地用流感病毒或……污染。结果显示，Si-QAC涂层的PPE中流感病毒和……滴度显著降低；这些抗菌效果持续了7天。这表明这种表面涂层消毒剂能有效减少PPE上的病原体污染，使其能够安全长期使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e070/7445321/55dccc692f8b/cevr-9-174-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e070/7445321/3b4e4715b6e6/cevr-9-174-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e070/7445321/6a6712e4f4bc/cevr-9-174-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e070/7445321/55dccc692f8b/cevr-9-174-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e070/7445321/3b4e4715b6e6/cevr-9-174-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e070/7445321/6a6712e4f4bc/cevr-9-174-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e070/7445321/55dccc692f8b/cevr-9-174-g003.jpg

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本文引用的文献

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2
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Front Med. 2020 Apr;14(2):113-116. doi: 10.1007/s11684-020-0758-9. Epub 2020 Mar 14.
3
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Emergent Mater. 2021;4(1):131-141. doi: 10.1007/s42247-021-00163-z. Epub 2021 Feb 3.
BMJ. 2020 Mar 4;368:m869. doi: 10.1136/bmj.m869.
4
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J Med Virol. 2020 Jun;92(6):602-611. doi: 10.1002/jmv.25731. Epub 2020 Mar 11.
5
Effectiveness of surface coatings containing silver ions in bacterial decontamination in a recovery unit.含银离子表面涂层在康复单元细菌净化中的有效性
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6
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7
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9
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