Kong Heng, Chen JiXin, Tang Shou-Ching
Department of Thyroid and Breast Surgery, Baoan Central Hospital of Shenzhen (Fifth Affiliated Hospital of Shenzhen University), Shenzhen City, Guangdong Province, China.
Department of General Surgery, Shenzhen University General Hospital, Shenzhen University, Shenzhen City, Guangdong Province, China.
J Int Med Res. 2020 Aug;48(8):300060520948710. doi: 10.1177/0300060520948710.
A 48-year-old woman was admitted to our hospital with a lump in her left breast. She was diagnosed with synchronous papillary thyroid carcinoma and breast ductal carcinoma. The patient underwent four cycles of neoadjuvant chemotherapy with epirubicin and cyclophosphamide, and one cycle of docetaxel. She then underwent left breast mastectomy and radical resection of thyroid cancer (total thyroidectomy and bilateral central group [levels VI and VII] lymph node dissection) at the same time. She was administered three cycles of chemotherapy with docetaxel and radiotherapy. The patient had no metastasis in the follow-up period. A literature search was performed to characterize the epidemiology, etiology, management, and prognosis of this condition. We speculate that hormone treatment could be a probable pathogenesis of synchronous breast and thyroid cancers.
一名48岁女性因左乳肿块入院。她被诊断为同步性甲状腺乳头状癌和乳腺导管癌。该患者接受了四个周期的表柔比星和环磷酰胺新辅助化疗，以及一个周期的多西他赛化疗。随后，她同时接受了左乳乳房切除术和甲状腺癌根治性切除术（全甲状腺切除术和双侧中央组[第六和第七区]淋巴结清扫术）。她又接受了三个周期的多西他赛化疗和放疗。随访期间患者无转移。进行文献检索以描述这种疾病的流行病学、病因、治疗和预后。我们推测激素治疗可能是同步性乳腺癌和甲状腺癌的一种可能发病机制。
