Department of Biomedical Systems and Informatics Engineering, Hijjawi Faculty for Engineering Technology, Yarmouk University, P.O.Box 21163, Irbid, Jordan.
Department of Electronics Engineering, Hijjawi Faculty for Engineering Technology, Yarmouk University, P.O.Box 21163, Irbid, Jordan.
Phys Eng Sci Med. 2020 Dec;43(4):1207-1217. doi: 10.1007/s13246-020-00923-x. Epub 2020 Aug 31.
The Photoplethysmogram (PPG) signal is one of the most important vital signals in biomedical applications. The non-invasive property and the convenience in the acquisition of both PPG and Piezoelectric Plethysmogram (PZPG) signals are considered as powerful and accurate tools for biomedical diagnosing applications, such as oxygen saturation in blood, blood flow, and blood pressure measurements. In this paper, a number of features for PPG and PZPG signals (ex. first derivative, second derivative, area under the curve and the ratio of systolic area to the diastolic area) are acquired and compared. The results show that both systems are able to extract the pulse rate (PR) and pulse rate variability (PRV), accurately with an estimation error of less than 10%. The averaged standard deviation of the ratio of the systolic area to the diastolic area for the first derivative of PPG and PZPG signals was small with less than 0.49 and 0.69 for the PPG and PZPG, respectively. Statistical analysis techniques (such as cross-correlation, P-value test, and Bland Altman method) are performed to address the relation between the PPG and PZPG signals. All of these methods showed a strong relationship between the features of the two signals (i.e. PPG and PZPG). The correlation value is found to be 0.954 with a p-value of < 0.05. This opens possibilities for combining both the PPG and PZPG systems to extract more features that can be used in diagnosing cardiovascular diseases. Such a system can provide a possibility to reduce the number of devices connected to patients (especially in emergencies) by means of measuring simultaneously both signals (PZPG and PPG).
光体积描记图(PPG)信号是生物医学应用中最重要的生命信号之一。PPG 和压电体积描记图(PZPG)信号的非侵入性和采集方便性被认为是生物医学诊断应用的强大而准确的工具,例如血氧饱和度、血流和血压测量。在本文中,获取并比较了 PPG 和 PZPG 信号的多个特征(例如一阶导数、二阶导数、曲线下面积和收缩期面积与舒张期面积的比值)。结果表明,这两个系统都能够准确地提取脉搏率(PR)和脉搏率变异性(PRV),估计误差小于 10%。PPG 和 PZPG 信号一阶导数的收缩期面积与舒张期面积比值的平均标准差较小,分别小于 0.49 和 0.69。本文采用了交叉相关、P 值检验和 Bland Altman 方法等统计分析技术来研究 PPG 和 PZPG 信号之间的关系。所有这些方法都显示出两个信号(即 PPG 和 PZPG)特征之间存在很强的关系(即 PPG 和 PZPG)。相关值为 0.954,p 值<0.05。这为结合 PPG 和 PZPG 系统提取更多可用于诊断心血管疾病的特征开辟了可能性。这样的系统可以通过同时测量两个信号(PZPG 和 PPG)来减少连接到患者的设备数量(特别是在紧急情况下)。