Komori Keisuke, Kano Kazuki, Aoyama Toru, Hashimoto Itaru, Hara Kentaro, Murakawa Masaaki, Atsumi Yosuke, Maezawa Yukio, Kazama Keisuke, Numata Masakatsu, Tamagawa Hiroshi, Yukawa Norio, Oshima Takashi, Masuda Munetaka, Rino Yasushi
Department of Surgery, Yokohama City University, Yokohama, Japan.
Department of Surgery, Kanagawa Cancer Center, Yokohama, Japan.
In Vivo. 2020 Sep-Oct;34(5):2697-2703. doi: 10.21873/invivo.12090.
The short- and long-term outcomes of gastrectomy in elderly patients with gastric cancer have not been fully evaluated.
Patients who underwent gastrectomy were classified into two groups: Non-elderly patients (<80 years old) and elderly patients (≥80 years old). The surgical morbidity, overall and cancer-specific survival in the two groups were compared.
A total of 411 patients were evaluated. The rate of overall complication was 29.4% in the non-elderly and 32.4% in the elderly (p=0.699). In the elderly, the overall and cancer-specific survival rates at 5 years after surgery were inferior to those of the younger group (59.8% vs. 66.7%, p=0.103 and 67.9% vs. 78.2%, p=0.028, respectively).
The short-term outcomes after gastrectomy were almost equal for the two groups in the present study. The prognosis was poor in elderly patients, especially those with advanced gastric cancer.
老年胃癌患者胃切除术后的短期和长期结局尚未得到充分评估。
接受胃切除术的患者分为两组：非老年患者（<80岁）和老年患者（≥80岁）。比较两组患者的手术并发症发生率、总生存率和癌症特异性生存率。
共评估了411例患者。非老年患者的总体并发症发生率为29.4%，老年患者为32.4%（p = 0.699）。老年患者术后5年的总生存率和癌症特异性生存率均低于年轻组（分别为59.8%对66.7%，p = 0.103；67.9%对78.2%，p = 0.028）。
本研究中两组患者胃切除术后的短期结局几乎相同。老年患者的预后较差，尤其是晚期胃癌患者。
