• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

尽管严重急性呼吸综合征冠状病毒2(SARS-CoV-2)在上呼吸道持续存在,但无精液排出该病毒的证据。

No Evidence of SARS-CoV-2 Seminal Shedding Despite SARS-CoV-2 Persistence in the Upper Respiratory Tract.

作者信息

Rawlings Stephen A, Ignacio Caroline, Porrachia Magali, Du Pinyi, Smith Davey M, Chaillon Antoine

机构信息

Division of Infectious Diseases and Global Public Health, University of California San Diego, San Diego, California, USA.

出版信息

Open Forum Infect Dis. 2020 Aug 7;7(8):ofaa325. doi: 10.1093/ofid/ofaa325. eCollection 2020 Aug.

DOI:10.1093/ofid/ofaa325
PMID:32875005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7452368/
Abstract

RNA viruses (eg, Zika, Ebola, HIV) are often shed in male genital secretions. We evaluated the presence and level of SARS-CoV-2 RNA in semen, nasal secretion, and saliva collected after confirmed infection. SARS-CoV-2 RNA was not detected in semen 6-17 days after the onset of symptoms despite concomitant shedding in oral secretions.

摘要

RNA病毒(如寨卡病毒、埃博拉病毒、艾滋病毒)通常会在男性生殖分泌物中排出。我们评估了确诊感染后采集的精液、鼻腔分泌物和唾液中SARS-CoV-2 RNA的存在情况及水平。尽管口腔分泌物中同时存在病毒排出,但在症状出现后6至17天的精液中未检测到SARS-CoV-2 RNA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf87/7452368/0e96efda2685/ofaa325f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf87/7452368/0e96efda2685/ofaa325f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf87/7452368/0e96efda2685/ofaa325f0001.jpg

相似文献

1
No Evidence of SARS-CoV-2 Seminal Shedding Despite SARS-CoV-2 Persistence in the Upper Respiratory Tract.尽管严重急性呼吸综合征冠状病毒2(SARS-CoV-2)在上呼吸道持续存在,但无精液排出该病毒的证据。
Open Forum Infect Dis. 2020 Aug 7;7(8):ofaa325. doi: 10.1093/ofid/ofaa325. eCollection 2020 Aug.
2
Comparative analysis of viral infection outcomes in human seminal fluid from prior viral epidemics and Sars-CoV-2 may offer trends for viral sexual transmissibility and long-term reproductive health implications.对既往病毒流行和 SARS-CoV-2 时期人类精液中病毒感染结局进行比较分析,可能为病毒的性传播趋势及其对长期生殖健康的影响提供依据。
Reprod Health. 2021 Jun 10;18(1):123. doi: 10.1186/s12978-021-01172-1.
3
Implications of RNA Viruses in the Male Reproductive Tract: An Outlook on SARS-CoV-2.RNA病毒在男性生殖道中的影响:关于严重急性呼吸综合征冠状病毒2的展望
Front Microbiol. 2021 Dec 24;12:783963. doi: 10.3389/fmicb.2021.783963. eCollection 2021.
4
Detection of Simian Immunodeficiency Virus in Semen, Urethra, and Male Reproductive Organs during Efficient Highly Active Antiretroviral Therapy.高效抗逆转录病毒治疗期间精液、尿道及男性生殖器官中猴免疫缺陷病毒的检测
J Virol. 2015 Jun;89(11):5772-87. doi: 10.1128/JVI.03628-14. Epub 2015 Apr 1.
5
Shedding of HIV-1 subtype E in semen and cervico-vaginal fluid.HIV-1 E亚型在精液和宫颈阴道液中的脱落。
J Med Assoc Thai. 1997 Jun;80(6):348-57.
6
Assessment of SARS-CoV-2 RNA shedding in semen of 36 males with symptomatic, asymptomatic, and convalescent infection during the first and second wave of COVID-19 pandemic in Italy.评估 SARS-CoV-2 RNA 在意大利 COVID-19 大流行第一波和第二波期间 36 名有症状、无症状和恢复期感染男性精液中的脱落情况。
Asian J Androl. 2022 Mar-Apr;24(2):135-138. doi: 10.4103/aja2021103.
7
Zika virus dynamics in body fluids and risk of sexual transmission in a non-endemic area.在非流行地区体液中的寨卡病毒动力学和性传播风险。
Trop Med Int Health. 2018 Jan;23(1):92-100. doi: 10.1111/tmi.13019. Epub 2017 Dec 21.
8
Evaluation of SARS-CoV-2 in semen, seminal plasma, and spermatozoa pellet of COVID-19 patients in the acute stage of infection.评估 SARS-CoV-2 在 COVID-19 感染急性期患者精液、精浆和精子中的存在情况。
PLoS One. 2021 Dec 14;16(12):e0260187. doi: 10.1371/journal.pone.0260187. eCollection 2021.
9
SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study.果蝠、雪貂、猪和鸡中 SARS-CoV-2:一项实验性传播研究。
Lancet Microbe. 2020 Sep;1(5):e218-e225. doi: 10.1016/S2666-5247(20)30089-6. Epub 2020 Jul 7.
10
COVID-19 disease in clinical setting: impact on gonadal function, transmission risk, and sperm quality in young males.临床环境中的 COVID-19 疾病:对年轻男性性腺功能、传播风险和精子质量的影响。
J Basic Clin Physiol Pharmacol. 2021 Oct 29;33(1):97-102. doi: 10.1515/jbcpp-2021-0227.

引用本文的文献

1
SARS-CoV-2 in semen: a multicenter prospective study and literature review.精液中的严重急性呼吸综合征冠状病毒2型:一项多中心前瞻性研究及文献综述
Basic Clin Androl. 2024 Dec 2;34(1):24. doi: 10.1186/s12610-024-00236-z.
2
A Systemic Review and Meta-analysis of the Effect of SARS-CoV-2 Infection on Sperm Parameters.新型冠状病毒2019感染对精子参数影响的系统评价与荟萃分析
Research (Wash D C). 2022 Jul 13;2022:9835731. doi: 10.34133/2022/9835731. eCollection 2022.
3
COVID-19 and Male Infertility: Is There a Role for Antioxidants?新冠病毒与男性不育:抗氧化剂能发挥作用吗?

本文引用的文献

1
No evidence of severe acute respiratory syndrome-coronavirus 2 in semen of males recovering from coronavirus disease 2019.从新冠肺炎康复男性的精液中未检测到严重急性呼吸综合征冠状病毒 2。
Fertil Steril. 2020 Jun;113(6):1135-1139. doi: 10.1016/j.fertnstert.2020.04.024. Epub 2020 Apr 17.
2
Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab.志愿者鼻咽拭子检测呈阳性样本中 SARS-CoV-2 在精液和尿液样本中的研究。
J Endocrinol Invest. 2020 Dec;43(12):1819-1822. doi: 10.1007/s40618-020-01261-1. Epub 2020 Apr 23.
3
Absence of 2019 novel coronavirus in semen and testes of COVID-19 patients†.
Antioxidants (Basel). 2023 Jul 25;12(8):1483. doi: 10.3390/antiox12081483.
4
Mild COVID-19 has no detrimental effect on semen quality.轻度新冠病毒感染对精液质量没有不利影响。
Basic Clin Androl. 2023 Jun 15;33(1):15. doi: 10.1186/s12610-023-00190-2.
5
Urological complications of COVID-19: a systematic review.新型冠状病毒肺炎的泌尿系统并发症:系统评价。
Int Braz J Urol. 2023 Jan-Feb;49(1):24-40. doi: 10.1590/S1677-5538.IBJU.2022.0281.
6
Infection of SARS-CoV-2 causes severe pathological changes in mouse testis.SARS-CoV-2 感染导致小鼠睾丸严重病变。
J Genet Genomics. 2023 Feb;50(2):99-107. doi: 10.1016/j.jgg.2022.11.011. Epub 2022 Dec 6.
7
Alterations in Human Semen After Infection with SARS-CoV-2: A Meta-analysis.感染新型冠状病毒2后人类精液的变化:一项荟萃分析。
J Reprod Infertil. 2022 Jul-Sep;23(3):199-206. doi: 10.18502/jri.v23i3.10011.
8
SARS-CoV-2, fertility and assisted reproduction.SARS-CoV-2,生育能力与辅助生殖。
Hum Reprod Update. 2023 Mar 1;29(2):177-196. doi: 10.1093/humupd/dmac037.
9
Validation of a SARS-CoV-2 RT-PCR assay: a requirement to evaluate viral contamination in human semen.SARS-CoV-2 RT-PCR assay 的验证:评估人类精液中病毒污染的必要条件。
Reprod Biomed Online. 2022 Dec;45(6):1247-1254. doi: 10.1016/j.rbmo.2022.09.004. Epub 2022 Sep 6.
10
Male Reproductive Tract Involvement and Sperm Parameters in SARS-CoV-2 Patients: A Systematic Review and Meta-Analysis.新冠病毒患者的男性生殖道受累情况及精子参数:一项系统评价和荟萃分析
World J Mens Health. 2023 Jul;41(3):538-557. doi: 10.5534/wjmh.220019. Epub 2022 Aug 17.
2019新型冠状病毒在新冠肺炎患者精液及睾丸中的缺失†
Biol Reprod. 2020 Jun 23;103(1):4-6. doi: 10.1093/biolre/ioaa050.
4
Temporal dynamics in viral shedding and transmissibility of COVID-19.新冠病毒脱落和传播的时间动态。
Nat Med. 2020 May;26(5):672-675. doi: 10.1038/s41591-020-0869-5. Epub 2020 Apr 15.
5
scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells.单细胞 RNA 测序分析人类睾丸组织揭示 ACE2 受体的存在,该受体可能是 SARS-CoV-2 感染精原细胞、间质细胞和支持细胞的靶标。
Cells. 2020 Apr 9;9(4):920. doi: 10.3390/cells9040920.
6
Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients.新冠康复患者体内病毒 RNA 的持续存在与清除。
Chin Med J (Engl). 2020 May 5;133(9):1039-1043. doi: 10.1097/CM9.0000000000000774.
7
Comparison of different samples for 2019 novel coronavirus detection by nucleic acid amplification tests.比较不同样本的核酸扩增检测用于 2019 新型冠状病毒检测。
Int J Infect Dis. 2020 Apr;93:264-267. doi: 10.1016/j.ijid.2020.02.050. Epub 2020 Feb 27.
8
High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa.2019-nCoV 对口腔黏膜上皮细胞 ACE2 受体的高表达。
Int J Oral Sci. 2020 Feb 24;12(1):8. doi: 10.1038/s41368-020-0074-x.
9
Structure analysis of the receptor binding of 2019-nCoV.2019新型冠状病毒受体结合的结构分析
Biochem Biophys Res Commun. 2020 Feb 17;525(1):135-40. doi: 10.1016/j.bbrc.2020.02.071.
10
Highly precise measurement of HIV DNA by droplet digital PCR.通过液滴数字 PCR 进行高度精确的 HIV DNA 测量。
PLoS One. 2013;8(4):e55943. doi: 10.1371/journal.pone.0055943. Epub 2013 Apr 3.