School of Biological & Population Health, College of Public Health & Human Sciences, Oregon State University, Corvallis, OR, USA.
Department of Public Health Sciences, School of Medicine & Dentistry, University of Rochester, Rochester, NY, USA.
Int J Epidemiol. 2021 Jan 23;49(6):1883-1896. doi: 10.1093/ije/dyaa115.
Recent advancements in drilling technology led to a rapid increase in natural gas development (NGD). Air pollution may be elevated in these areas and may vary by drilling type (conventional and unconventional), production volume and gas flaring. Impacts of NGD on paediatric asthma are largely unknown. This study quantifies associations between specific NGD activities and paediatric asthma hospitalizations in Texas.
We leveraged a database of Texas inpatient hospitalizations between 2000 and 2010 at the zip code level by quarter to examine associations between NGD and paediatric asthma hospitalizations, where our primary outcome is 0 vs ≥1 hospitalization. We used quarterly production reports to assess additional drilling-specific exposures at the zip code-level including drilling type, production and gas flaring. We developed logistic regression models to assess paediatric asthma hospitalizations by zip code-quarter-year observations, thus capturing spatiotemporal exposure patterns.
We observed increased odds of ≥1 paediatric asthma hospitalization in a zip code per quarter associated with increasing tertiles of NGD exposure and show that spatiotemporal variation impacts results. Conventional drilling, compared with no drilling, is associated with odds ratios up to 1.23 [95% confidence interval (CI): 1.13, 1.34], whereas unconventional drilling is associated with odds ratios up to 1.59 (95% CI: 1.46, 1.73). Increasing production volumes are associated with increased paediatric asthma hospitalizations in an exposure-response relationship, whereas associations with flaring volumes are inconsistent.
We found evidence of associations between paediatric asthma hospitalizations and NGD, regardless of drilling type. Practices related to production volume may be driving these positive associations.
最近钻井技术的进步导致天然气开发(NGD)迅速增加。这些地区的空气污染可能会加剧,并可能因钻井类型(常规和非常规)、产量和天然气燃烧而有所不同。NGD 对儿科哮喘的影响在很大程度上尚不清楚。本研究量化了德克萨斯州特定 NGD 活动与儿科哮喘住院之间的关联。
我们利用了德克萨斯州 2000 年至 2010 年按季度划分的住院患者数据库,研究了 NGD 与儿科哮喘住院之间的关联,我们的主要结果是 0 次与≥1 次住院。我们使用季度生产报告评估了邮政编码级别的额外钻井特定暴露,包括钻井类型、产量和天然气燃烧。我们开发了逻辑回归模型,以评估邮政编码季度年观测值的儿科哮喘住院情况,从而捕捉时空暴露模式。
我们观察到,与 NGD 暴露增加相关的每季度邮政编码中,儿科哮喘住院的可能性增加,并且表明时空变化会影响结果。与无钻井相比,常规钻井与高达 1.23 的优势比(95%置信区间:1.13,1.34)相关,而非常规钻井与高达 1.59 的优势比(95%置信区间:1.46,1.73)相关。产量增加与儿科哮喘住院呈暴露反应关系,而与燃烧量的关联则不一致。
我们发现儿科哮喘住院与 NGD 之间存在关联,无论钻井类型如何。与产量相关的实践可能是导致这些正相关的原因。