Liang Lili, Ahamed Ashiq, Ge Liya, Fu Xiaoxu, Lisak Grzegorz
Nanyang Technological University, School of Civil and Environmental Engineering, SINGAPORE.
Nanyang Technological University, School of Civil and Environmental Engineering, 50 nanyang Avenue, 639804, Singapore, SINGAPORE.
Chempluschem. 2020 Aug 21;85(9):2105-28. doi: 10.1002/cplu.202000460.
The rise in human pandemics demands prudent approaches in antiviral material development for disease prevention and treatment via effective protective equipment and therapeutic strategy. However, the current state of the antiviral materials research is predominantly aligned towards drug development and its related areas, catering to the field of pharmaceutical technology. This review distinguishes the research advances in terms of innovative materials exhibiting antiviral activities that take advantage of fast-developing nanotechnology and biopolymer technology. Essential concepts of antiviral principles and underlying mechanisms are illustrated, followed with detailed descriptions of novel antiviral materials including inorganic nanomaterials, organic nanomaterials and biopolymers. The biomedical applications of the antiviral materials are also elaborated based on the specific categorization. Challenges and future prospects are discussed to facilitate the research and development of protective solutions and curative treatments.
人类大流行疾病的增加要求在抗病毒材料开发方面采取审慎的方法,通过有效的防护设备和治疗策略来预防和治疗疾病。然而,目前抗病毒材料的研究主要集中在药物开发及其相关领域,服务于制药技术领域。本综述区分了利用快速发展的纳米技术和生物聚合物技术展现出抗病毒活性的创新材料方面的研究进展。阐述了抗病毒原理和潜在机制的基本概念,随后详细描述了新型抗病毒材料,包括无机纳米材料、有机纳米材料和生物聚合物。还根据具体分类阐述了抗病毒材料的生物医学应用。讨论了挑战和未来前景,以促进防护解决方案和治疗方法的研发。