Su Shi, M Kang Peter
Cardiovascular Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, 3 Blackfan Circle, CLS 910, Boston, MA 02215, USA.
Pharmaceutics. 2020 Sep 1;12(9):837. doi: 10.3390/pharmaceutics12090837.
Nanotechnologies have attracted increasing attention in their application in medicine, especially in the development of new drug delivery systems. With the help of nano-sized carriers, drugs can reach specific diseased areas, prolonging therapeutic efficacy while decreasing undesired side-effects. In addition, recent nanotechnological advances, such as surface stabilization and stimuli-responsive functionalization have also significantly improved the targeting capacity and therapeutic efficacy of the nanocarrier assisted drug delivery system. In this review, we evaluate recent advances in the development of different nanocarriers and their applications in therapeutics delivery.
纳米技术在医学应用中越来越受到关注，尤其是在新型药物递送系统的开发方面。借助纳米级载体，药物能够到达特定的患病区域，延长治疗效果，同时减少不良副作用。此外，最近的纳米技术进展，如表面稳定化和刺激响应功能化，也显著提高了纳米载体辅助药物递送系统的靶向能力和治疗效果。在本综述中，我们评估了不同纳米载体开发的最新进展及其在治疗递送中的应用。
