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腓骨近端截骨术对伴内翻畸形的轻度膝关节骨关节炎应力变化的影响:有限元分析。

Effects of proximal fibular osteotomy on stress changes in mild knee osteoarthritis with varus deformity: a finite element analysis.

机构信息

The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, China.

The Lab of Orthopaedics of Chinese Medicine of Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, China.

出版信息

J Orthop Surg Res. 2020 Sep 3;15(1):375. doi: 10.1186/s13018-020-01894-1.

Abstract

BACKGROUND

Many previous studies lack sufficient quantitative evidences about changes in biomechanical properties of the knee in response to proximal fibular osteotomy (PFO). Therefore, the aim of this study was to compare the preoperative and postoperative effects of PFO on mechanical stresses in the knee joint and provide with a biomechanical basis for PFO in the treatment of mild knee osteoarthritis (KOA) with varus deformity.

METHODS

A total of 10 patients suffering mild KOA with varus deformity were enrolled in this study. Their image data from computerized tomography (CT) and magnetic resonance imaging (MRI) were used for finite element models, and PFO models were established. Static structural analysis was carried out using ABAQUS to compare the von Mises stress distribution and values of the maximal von Mises stress of femoral cartilage, meniscuses, tibial cartilages, and tibial plateau before and after surgery.

RESULTS

The stress distribution in the cortical bone of the tibial plateau showed that stresses were transferred from the anterior medial area to the posterior medial area after PFO. Values of the maximal von Mises stress in femoral cartilage, medial meniscus, medial tibial cartilage, and tibial plateau after surgery were significantly lower than the preoperative values, with statistically significant differences (P < 0.05). Postoperative values of the maximal von Mises stress of lateral meniscus and lateral tibial cartilage were significantly higher than the preoperative ones, with statistically significant differences (P < 0.05).

CONCLUSION

PFO could reduce the stresses in the medial compartment of the knee joint with stress pathways transferring from the anterior medial area to the posterior medial area of the tibial plateau. Therefore, PFO is recommended for the treatment of mild KOA with varus deformity featuring favorably pain-relieving effects.

摘要

背景

许多先前的研究缺乏关于腓骨近端截骨术(PFO)对膝关节生物力学特性变化的充分定量证据。因此,本研究旨在比较 PFO 对膝关节机械应力的术前和术后影响,并为 PFO 治疗伴内翻畸形的轻度膝骨关节炎(KOA)提供生物力学依据。

方法

本研究共纳入 10 例伴内翻畸形的轻度 KOA 患者。他们的计算机断层扫描(CT)和磁共振成像(MRI)图像数据用于有限元模型,并建立 PFO 模型。使用 ABAQUS 进行静态结构分析,比较手术前后股骨软骨、半月板、胫骨软骨和胫骨平台的 von Mises 应力分布和最大 von Mises 应力值。

结果

胫骨平台皮质骨的应力分布表明,PFO 后应力从内侧前区转移到内侧后区。术后股骨软骨、内侧半月板、内侧胫骨软骨和胫骨平台的最大 von Mises 应力值明显低于术前,差异有统计学意义(P<0.05)。术后外侧半月板和外侧胫骨软骨的最大 von Mises 应力值明显高于术前,差异有统计学意义(P<0.05)。

结论

PFO 可减少膝关节内侧间室的应力,使应力路径从胫骨平台的内侧前区转移到内侧后区。因此,PFO 推荐用于治疗伴内翻畸形的轻度 KOA,具有较好的止痛效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a51/7469409/fcb54ae6c428/13018_2020_1894_Fig1_HTML.jpg

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