Chen Hao, Jia Weidong
Department of Hepatic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, HeFei, Anhui, 230001, China.
Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, HeFei, Anhui, 230001, China.
Genes Dis. 2020 Mar 28;7(3):320-327. doi: 10.1016/j.gendis.2020.02.001. eCollection 2020 Sep.
The global incidence of liver cancer continues to grow. Liver cancer, especially hepatocellular carcinoma, has high recurrence and mortality rates. Here, we review the past decade's diagnostic, therapeutic, and management strategies for hepatocellular carcinoma, and summarize new patient management approaches, including enhanced recovery after surgery, targeted therapy, and immunotherapy. We compare traditional and innovative management methods, which comprise developments in precision medicine, and consider their limitations. Ongoing innovation and technological advances enable surgeons to gain deeper understandings of the multidimensionality of hepatocellular carcinoma, thereby promoting the continuous development of precision therapy.
全球肝癌发病率持续上升。肝癌,尤其是肝细胞癌,具有高复发率和高死亡率。在此,我们回顾过去十年肝细胞癌的诊断、治疗及管理策略,并总结新的患者管理方法,包括术后加速康复、靶向治疗和免疫治疗。我们比较传统和创新管理方法,其中包括精准医学的发展,并考量它们的局限性。持续的创新和技术进步使外科医生能够更深入地理解肝细胞癌的多维度特性,从而推动精准治疗的不断发展。