Ng Caleb C, Jumper J Michael, Cunningham Emmett T
The Department of Ophthalmology, California Pacific Medical Center, San Francisco, CA, USA.
West Coast Retina Medical Group, San Francisco, CA, USA.
Am J Ophthalmol Case Rep. 2020 Aug 3;19:100845. doi: 10.1016/j.ajoc.2020.100845. eCollection 2020 Sep.
To describe the multimodal imaging (MMI) findings and clinical course of a case of Multiple Evanescent White Dot Syndrome (MEWDS) following immunization with inactivated intra-dermal influenza virus, and to explore whether similarities exist with other, previously reported cases.
A 34-year-old Caucasian man presented with unilateral onset of para-central scotomata, photopsias, and dyschromatopsia two weeks after administration of an influenza vaccine. Clinical examination and MMI were indicative of MEWDS. The patient's MMI abnormalities and symptoms resolved spontaneously after four weeks.
This is the first reported case of MMI of post-influenza vaccination-associated MEWDS. Comparison with eight previously reported cases of MEWDS following various immunizations revealed that subjects tended to be healthy, young to middle age women with a median time to onset of two weeks. Vision tended to recover spontaneously over one to three months.
描述1例接种灭活皮内流感病毒疫苗后发生多发性一过性白点综合征（MEWDS）患者的多模态成像（MMI）表现及临床病程，并探讨其与既往报道的其他病例是否存在相似之处。
一名34岁的白人男性在接种流感疫苗两周后出现单侧中央旁暗点、闪光幻觉和色觉障碍。临床检查和MMI提示为MEWDS。患者的MMI异常和症状在四周后自发缓解。
这是首例关于流感疫苗接种后相关MEWDS的MMI报道病例。与既往报道的8例各种免疫接种后发生MEWDS的病例相比，发现患者多为健康的中青年女性，发病中位时间为两周。视力往往在1至3个月内自发恢复。
