Department of Nutrition, Universidade de São Paulo (USP), São Paulo, Brazil.
Department of Physical Education, Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP), Presidente Prudente, Brazil.
Am J Hum Biol. 2021 May;33(3):e23492. doi: 10.1002/ajhb.23492. Epub 2020 Sep 4.
To analyze the association between body mass index trajectories and non-communicable diseases (NCDs) in women, and the interaction effects of leisure time physical activity on this relationship.
Sample was composed by 15 628 women (≥30 years old) who performed objective measurement of body mass, height, and blood pressure in the 2013 Brazilian Health Survey (2013). Information regarding the body mass at 20 years old, current type 2 diabetes (T2DM), dyslipidemia diagnosis, and leisure time physical activity were self-reported by the participants. Socio-demographic and behavioral covariates were considered. Logistic regression models were used for the statistical analysis.
Those who were obese in both moments and women who become obese showed similar high risk, however, the prevalence of NCDs among women who were no longer obese was similar to the consistently non-obese. Leisure time physical activity attenuated the general deleterious effect of obesity, especially among the consistently obese women for dyslipidemia (inactive: OR: 2.02 [95%CI: 1.69-2.43] vs active: OR: 1.05 [95%CI: 0.55-1.99]), T2DM (inactive: OR: 3.84 [95%CI: 2.72-5.43] vs active: OR: 4.38 [95%CI: 1.49-12.86]) and high blood pressure (inactive: OR: 2.00 [95%CI: 1.56-2.57] vs active: OR: 1.15 [95%CI: 0.57-2.52]).
Changes in body mass index appear to be sensitive to detecting the risk of NCDs over lifespan. In addition, leisure time physical activity attenuates the negative effects of obesity on NCDs, but this appears more important for the consistently non-obese women.
分析女性体重指数轨迹与非传染性疾病（NCD）之间的关系，并分析休闲时间体力活动对这种关系的交互作用。
本研究样本由 15628 名（≥30 岁）在 2013 年巴西健康调查（2013）中进行了身体质量、身高和血压的客观测量的女性组成。参与者自我报告了 20 岁时的体重、当前 2 型糖尿病（T2DM）、血脂异常诊断和休闲时间体力活动的信息。考虑了社会人口统计学和行为学协变量。使用逻辑回归模型进行统计分析。
在两个时间点都肥胖的女性和体重增加的女性具有相似的高风险，但不再肥胖的女性的 NCD 患病率与一直非肥胖的女性相似。休闲时间体力活动减轻了肥胖的普遍不良影响，尤其是在一直肥胖的女性中，对血脂异常（不活动：OR：2.02 [95%CI：1.69-2.43] vs 活动：OR：1.05 [95%CI：0.55-1.99]）、T2DM（不活动：OR：3.84 [95%CI：2.72-5.43] vs 活动：OR：4.38 [95%CI：1.49-12.86]）和高血压（不活动：OR：2.00 [95%CI：1.56-2.57] vs 活动：OR：1.15 [95%CI：0.57-2.52]）的影响。
体重指数的变化似乎对检测一生中 NCD 的风险很敏感。此外，休闲时间体力活动减轻了肥胖对 NCD 的负面影响，但这对一直非肥胖的女性似乎更为重要。
