他汀类药物对新型冠状病毒肺炎患者影响的荟萃分析 - Suppr

Suppr

超能文献

Meta-analysis of Effect of Statins in Patients with COVID-19.

作者信息

Kow Chia Siang, Hasan Syed Shahzad

机构信息

School of Postgraduate Studies, International Medical University, Kuala Lumpur, Malaysia.

Department of Pharmacy, University of Huddersfield, Huddersfield, United Kingdom.

出版信息

Am J Cardiol. 2020 Nov 1;134:153-155. doi: 10.1016/j.amjcard.2020.08.004. Epub 2020 Aug 12.

DOI:10.1016/j.amjcard.2020.08.004

PMID:32891399

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7419280/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f71/7419280/4726ea9820b8/gr1_lrg.jpg

相似文献

Meta-analysis of Effect of Statins in Patients with COVID-19.他汀类药物对新型冠状病毒肺炎患者影响的荟萃分析

Am J Cardiol. 2020 Nov 1;134:153-155. doi: 10.1016/j.amjcard.2020.08.004. Epub 2020 Aug 12.

Are statins safe in patients with COVID-19?他汀类药物对新冠肺炎患者安全吗？

J Clin Lipidol. 2020 Jul-Aug;14(4):396-397. doi: 10.1016/j.jacl.2020.06.009. Epub 2020 Jun 22.

Potential role of statins in COVID-19.他汀类药物在 COVID-19 中的潜在作用。

Int J Infect Dis. 2020 Jul;96:615-617. doi: 10.1016/j.ijid.2020.05.115. Epub 2020 Jun 2.

Teaching Old Drugs New Tricks: Statins for COVID-19?老药新用：他汀类药物治疗 COVID-19？

Cell Metab. 2020 Aug 4;32(2):145-147. doi: 10.1016/j.cmet.2020.07.006.

Statins in coronavirus outbreak: It's time for experimental and clinical studies.冠状病毒爆发中的他汀类药物：是时候进行实验和临床研究了。

Pharmacol Res. 2020 Jun;156:104803. doi: 10.1016/j.phrs.2020.104803. Epub 2020 Apr 11.

Blocking angiotensin earlier with RAS blockers, statins, and heparin in high-risk COVID-19 patients: Is the remedy here?在高危COVID-19患者中早期使用肾素-血管紧张素系统（RAS）阻滞剂、他汀类药物和肝素阻断血管紧张素：这是解决办法吗？

Anatol J Cardiol. 2020 Jul;24(1):19-20. doi: 10.14744/AnatolJCardiol.2020.73232.

Use of statins in patients with COVID-19.他汀类药物在新冠肺炎患者中的应用。

QJM. 2020 Aug 1;113(8):604-605. doi: 10.1093/qjmed/hcaa172.

Response to: Use of statins in patients with COVID-19.回应：新冠病毒疾病患者使用他汀类药物的情况

QJM. 2020 Aug 1;113(8):606-607. doi: 10.1093/qjmed/hcaa173.

Targeting SARS-CoV-2 using polycomb inhibitors as antiviral agents.使用多梳蛋白抑制剂作为抗病毒药物靶向严重急性呼吸综合征冠状病毒2（SARS-CoV-2）

Epigenomics. 2020 May;12(10):811-812. doi: 10.2217/epi-2020-0154. Epub 2020 Jun 4.

Considerations for Statin Therapy in Patients with COVID-19.新型冠状病毒肺炎患者他汀类药物治疗的考量因素

Pharmacotherapy. 2020 May;40(5):484-486. doi: 10.1002/phar.2397. Epub 2020 May 4.

引用本文的文献

Metabolic Reprogramming in Respiratory Viral Infections: A Focus on SARS-CoV-2, Influenza, and Respiratory Syncytial Virus.呼吸道病毒感染中的代谢重编程：聚焦于严重急性呼吸综合征冠状病毒2、流感病毒和呼吸道合胞病毒

Biomolecules. 2025 Jul 16;15(7):1027. doi: 10.3390/biom15071027.

In Vitro Investigation of Statin Effects on Genes Associated with Severe COVID-19 in Cancerous and Non-Cancerous Cells.他汀类药物对癌细胞和非癌细胞中与重症 COVID-19 相关基因影响的体外研究

Biomedicines. 2025 Jul 14;13(7):1714. doi: 10.3390/biomedicines13071714.

Do Statins Affect Viral Infections Encountered by International Travelers?他汀类药物会影响国际旅行者遭遇的病毒感染吗？

Trop Med Infect Dis. 2025 Mar 11;10(3):73. doi: 10.3390/tropicalmed10030073.

Lights and Shadows of Long COVID: Are Latent Infections the Real Hidden Enemy?长期新冠的光影：潜伏感染是真正的隐藏敌人吗？

J Clin Med. 2024 Nov 25;13(23):7124. doi: 10.3390/jcm13237124.

Atorvastatin and telmisartan do not reduce nasopharyngeal carriage of SARS-CoV-2 in mild or moderate COVID-19 in a phase IIb randomized controlled trial.阿托伐他汀和替米沙坦在一项 2b 期随机对照试验中不能降低轻度或中度 COVID-19 患者鼻咽部 SARS-CoV-2 的携带量。

Sci Rep. 2024 Oct 23;14(1):25028. doi: 10.1038/s41598-024-72449-1.

The Evaluation of Lipid-Lowering Treatment in Patients with Acute Coronary Syndrome in a Hungarian Invasive Centre in 2015, 2017, and during the COVID-19 Pandemic-The Comparison of the Achieved LDL-Cholesterol Values Calculated with Friedewald and Martin-Hopkins Methods.2015年、2017年及新冠疫情期间匈牙利一家介入治疗中心急性冠状动脉综合征患者降脂治疗的评估——Friedewald法与Martin-Hopkins法计算的低密度脂蛋白胆固醇达标值比较

J Clin Med. 2024 Jun 11;13(12):3398. doi: 10.3390/jcm13123398.

Statins-From Fungi to Pharmacy.他汀类药物——从真菌到药物制剂。

Int J Mol Sci. 2023 Dec 29;25(1):466. doi: 10.3390/ijms25010466.

A bibliometric analysis of PCSK9 inhibitors from 2007 to 2022.2007 年至 2022 年 PCSK9 抑制剂的文献计量分析。

Front Endocrinol (Lausanne). 2023 Nov 29;14:1218968. doi: 10.3389/fendo.2023.1218968. eCollection 2023.

Coronavirus Disease Vaccination Among Persons With Disabilities: Understanding Vaccine Perceptions and Hesitancy in Ghana.加纳残疾人的冠状病毒病疫苗接种：了解疫苗认知与犹豫情况

Linacre Q. 2023 Nov;90(4):452-471. doi: 10.1177/00243639231178626. Epub 2023 Jun 7.

Statin Use in Relation to COVID-19 and Other Respiratory Infections: Muscle and Other Considerations.他汀类药物的使用与新冠病毒病及其他呼吸道感染的关系：肌肉及其他考量因素

J Clin Med. 2023 Jul 13;12(14):4659. doi: 10.3390/jcm12144659.

本文引用的文献

Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy.意大利伦巴第地区重症监护病房中 COVID-19 患者死亡的相关危险因素。

JAMA Intern Med. 2020 Oct 1;180(10):1345-1355. doi: 10.1001/jamainternmed.2020.3539.

Atorvastatin associated with decreased hazard for death in COVID-19 patients admitted to an ICU: a retrospective cohort study.阿托伐他汀与入住重症监护病房的COVID-19患者死亡风险降低相关：一项回顾性队列研究。

Crit Care. 2020 Jul 14;24(1):429. doi: 10.1186/s13054-020-03154-4.

In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19.住院期间使用他汀类药物与 COVID-19 患者的死亡率降低相关。

Cell Metab. 2020 Aug 4;32(2):176-187.e4. doi: 10.1016/j.cmet.2020.06.015. Epub 2020 Jun 24.

Are certain drugs associated with enhanced mortality in COVID-19?某些药物是否与新冠病毒疾病（COVID-19）死亡率升高有关？

QJM. 2020 Jul 1;113(7):509-510. doi: 10.1093/qjmed/hcaa103.

Association of Elevated Plasma Interleukin-18 Level With Increased Mortality in a Clinical Trial of Statin Treatment for Acute Respiratory Distress Syndrome.血浆白细胞介素-18 水平升高与急性呼吸窘迫综合征他汀类药物治疗临床试验中死亡率增加的相关性。

Crit Care Med. 2019 Aug;47(8):1089-1096. doi: 10.1097/CCM.0000000000003816.

Statins May Decrease the Fatality Rate of Middle East Respiratory Syndrome Infection.他汀类药物可能降低中东呼吸综合征感染的死亡率。

mBio. 2015 Aug 11;6(4):e01120. doi: 10.1128/mBio.01120-15.

Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection.通过TRIF的Toll样受体3信号传导有助于对严重急性呼吸综合征冠状病毒感染产生保护性先天免疫反应。

mBio. 2015 May 26;6(3):e00638-15. doi: 10.1128/mBio.00638-15.

Atorvastatin attenuates myocardial remodeling induced by chronic intermittent hypoxia in rats: partly involvement of TLR-4/MYD88 pathway.阿托伐他汀减轻大鼠慢性间歇性低氧诱导的心肌重构：TLR-4/MYD88 通路的部分参与。

Biochem Biophys Res Commun. 2014 Mar 28;446(1):292-7. doi: 10.1016/j.bbrc.2014.02.091. Epub 2014 Feb 28.

Effects of rosuvastatin on expression of angiotensin-converting enzyme 2 after vascular balloon injury in rats.瑞舒伐他汀对大鼠血管球囊损伤后血管紧张素转换酶 2 表达的影响。

J Geriatr Cardiol. 2013 Jun;10(2):151-8. doi: 10.3969/j.issn.1671-5411.2013.02.009.

Requirements for CEACAMs and cholesterol during murine coronavirus cell entry.鼠冠状病毒进入细胞过程中对癌胚抗原相关细胞黏附分子（CEACAMs）和胆固醇的需求。

J Virol. 2004 Mar;78(6):2682-92. doi: 10.1128/jvi.78.6.2682-2692.2004.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验