成人中新型冠状病毒肺炎与吉兰-巴雷综合征的关系。系统评价。
Relation between COVID-19 and Guillain-Barré syndrome in adults. Systematic review.
作者信息
Trujillo Gittermann L M, Valenzuela Feris S N, von Oetinger Giacoman A
机构信息
Escuela de Kinesiología, Facultad de Ciencias de la Salud, Universidad de las Américas, Santiago, Chile; Escuela de Kinesiología, Facultad de Salud y Odontología, Universidad Diego Portales, Santiago, Chile.
Centro Médico Dental RedSalud, Maipú. Unidad de Kinesiología Ambulatoria, Santiago, Chile.
出版信息
Neurologia (Engl Ed). 2020 Nov-Dec;35(9):646-654. doi: 10.1016/j.nrl.2020.07.004. Epub 2020 Jul 24.
INTRODUCTION
Numerous cases have been reported of patients with symptoms of Guillain-Barré syndrome associated with COVID-19, but much information is still lacking on this association and its implications. The objective of this review is to analyse the available evidence on this topic in the adult population.
MATERIAL AND METHODS
A systematic review was conducted of studies published on scientific databases: PubMed, Cochrane, Science Direct, Medline, and WHO COVID-19 database.
RESULTS
We identified 47 studies, which were analysed and completed using the Covidence platform; the final analysis included 24 articles, with a total of 30 patients.
CONCLUSIONS
We found a strong association between both conditions; furthermore, the studies analysed highlight differences in the presentation of the disease, with greater severity of symptoms in Guillain-Barre syndrome associated with COVID-19.
引言
已有大量关于吉兰-巴雷综合征症状与COVID-19相关患者的病例报道，但关于这种关联及其影响仍缺乏很多信息。本综述的目的是分析成年人群中关于该主题的现有证据。
材料与方法
对发表在科学数据库（PubMed、Cochrane、Science Direct、Medline和WHO COVID-19数据库）上的研究进行了系统综述。
结果
我们识别出47项研究，使用Covidence平台对其进行了分析和完善；最终分析纳入了24篇文章，共30例患者。
结论
我们发现这两种情况之间存在很强的关联；此外，所分析的研究突出了疾病表现的差异，与COVID-19相关的吉兰-巴雷综合征症状更严重。
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