AP-HP, Groupe Hospitalier La Pitié-Salpêtrière, Service de Parasitologie-Mycologie, Paris, France
Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Paris, France.
Antimicrob Agents Chemother. 2020 Nov 17;64(12). doi: 10.1128/AAC.01374-20.
The antifungal susceptibility of cryptic species is poorly known. We assessed 51 isolates, belonging to seven cryptic species, by the EUCAST reference method and the concentration gradient strip (CGS) method. Species-specific patterns were observed, with high MICs for azole drugs, except for and , and high MICs for amphotericin B for and Essential and categorical agreements between EUCAST and CGS results were between 53.3 and 93.3%.
隐种的抗真菌药敏性知之甚少。我们采用 EUCAST 参考方法和浓度梯度条(CGS)法评估了属于七个隐种的 51 株分离株。观察到种特异性模式,除 和 外,唑类药物的 MIC 较高, 和 必需的两性霉素 B 的 MIC 也较高,EUCAST 和 CGS 结果之间的符合率为 53.3%至 93.3%。