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肩周炎与甲状腺疾病之间的关联:强化证据

Association between Frozen Shoulder and Thyroid Diseases: Strengthening the Evidences.

作者信息

Cohen Carina, Tortato Simone, Silva Otavio Bento Souza, Leal Mariana Ferreira, Ejnisman Benno, Faloppa Flavio

机构信息

Departamento de Ortopedia e Traumatologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

出版信息

Rev Bras Ortop (Sao Paulo). 2020 Aug;55(4):483-489. doi: 10.1055/s-0039-3402476. Epub 2020 Apr 6.

DOI:10.1055/s-0039-3402476
PMID:32904783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7458737/
Abstract

To clarify the association of thyroid disorders and primary frozen shoulder by comparing this group with controls without shoulder disease and with patients with rotator cuff tears.  We evaluated 166 patients who presented frozen shoulder with treatment in progress or already treated, which were compared with 129 patients with diagnosis of rotator cuff tears and 251 control subjects. All of the participants answered the questionnaire on the following variables: age, gender, body mass index (BMI), occupation, physical activity, presence of thyroid disorders and other comorbidities, smoking and use of alcohol.  When comparing the frozen shoulder group with the control and rotator cuff groups, there is a specific association between the presence of thyroid disorders and frozen shoulder. By calculating relative risk, it is possible to state that an individual with thyropathy has 2.69 more chance of developing frozen shoulder. Also, there was an association with gender, since women with frozen shoulder exceeded significantly the risk.  Thyroid disorders, especially hypothyroidism and the presence of benign thyroid nodules, are risk factors significantly associated with frozen shoulder, rising the chances to 2.69 times of developing frozen shoulder. This is the first study that uses, in addition to the control group, a second group with rotator cuff tears, so it was shown that there is a specific association of thyroid disorders and frozen shoulder, but not with shoulder disorders in general.

摘要

通过将该组患者与无肩部疾病的对照组以及肩袖撕裂患者进行比较,以阐明甲状腺疾病与原发性冻结肩之间的关联。我们评估了166例正在接受治疗或已经接受治疗的冻结肩患者,并将其与129例诊断为肩袖撕裂的患者和251例对照受试者进行比较。所有参与者都回答了关于以下变量的问卷:年龄、性别、体重指数(BMI)、职业、体育活动、甲状腺疾病和其他合并症的存在情况、吸烟和饮酒情况。当将冻结肩组与对照组和肩袖组进行比较时,甲状腺疾病的存在与冻结肩之间存在特定关联。通过计算相对风险,可以得出患有甲状腺疾病的个体患冻结肩的可能性高出2.69倍。此外,还与性别有关联,因为患有冻结肩的女性风险显著更高。甲状腺疾病,尤其是甲状腺功能减退和良性甲状腺结节的存在,是与冻结肩显著相关的风险因素,患冻结肩的几率增加到2.69倍。这是第一项除对照组外还使用肩袖撕裂患者作为第二组的研究,结果表明甲状腺疾病与冻结肩存在特定关联,但与一般肩部疾病无关。

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本文引用的文献

1
Prevalence of hypothyroidism in patients with frozen shoulder.肩周炎患者甲状腺功能减退症的患病率
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Adhesive capsulitis of the shoulder and diabetes: a meta-analysis of prevalence.肩部粘连性关节囊炎与糖尿病:患病率的荟萃分析
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