Noor Rashed, Maniha Syeda Muntaka
Department of Microbiology, School of Environment and Life Sciences (SELS), Independent University, Bangladesh (IUB), Plot 16, Block B, Aftabuddin Ahmed Road, Bashundhara, Dhaka, 1229 Bangladesh.
Virusdisease. 2020 Dec;31(4):441-449. doi: 10.1007/s13337-020-00628-5. Epub 2020 Sep 2.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently causing the respiratory illness termed as the coronavirus disease 2019 or the COVID-19 pandemic. Indeed, the significant increase in deaths in the current days due to influenza around the world started in 1889 is a continued public health threat because of its intermittent style of pandemic outbreaks. An array of research on the influenza viruses has been conducted especially pointing on (1) the development of the anti-viral drugs and the design of probable vaccines on trial basis, (2) the biochemical and genetic aspects underlying the viral pathogenicity, (3) the viral epidemiology, and on (4) the protective immunity against the influenza viruses. Current review briefly discussed the epidemic/ pandemic history of influenza and correlated with the current epidemiology, the possible preventive measures that may be taken by the public health professionals as well as to increase the protective awareness among the general people. The viral reassortments during the initiation of pandemics have also been focused based on the previous literatures.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）目前正在引发被称为2019冠状病毒病或COVID-19大流行的呼吸系统疾病。事实上，自1889年以来，全球范围内因流感导致的死亡人数显著增加，由于其大流行爆发的间歇性特点，这仍然是一个持续的公共卫生威胁。针对流感病毒已经开展了一系列研究，特别是针对以下方面：（1）抗病毒药物的研发以及试验性可能疫苗的设计；（2）病毒致病性背后的生化和遗传方面；（3）病毒流行病学；（4）针对流感病毒的保护性免疫。本综述简要讨论了流感的流行/大流行历史，并与当前的流行病学相关联，公共卫生专业人员可能采取的预防措施以及提高普通民众的防护意识。还根据以往文献重点探讨了大流行初期的病毒重配情况。
