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基于世界卫生组织核心药物使用指标的埃塞俄比亚西北部芬诺塞尔拉姆和阿西尔阿德泽维迪医院的合理用药实践。

Practice towards Rational Drug Use at Finotselam and Asirade Zewudie Hospitals Based on WHO Core Drug Use Indicators, Northwest Ethiopia.

机构信息

Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Finoteselam Hospital, Finote Selam, Ethiopia.

出版信息

ScientificWorldJournal. 2020 Aug 28;2020:1634294. doi: 10.1155/2020/1634294. eCollection 2020.

Abstract

BACKGROUND

The rational use of drugs requires that patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them and their community with full information and with the lowest possible cost. If one of these is not met, it is referred to as irrational drug use. Many drugs have been sold or prescribed inappropriately in the world, and a significant part of the world population lacks access to essential medicine. The aim of this study was to assess practice towards rational drug use at Finoteselam and Asirade Zewudie hospitals.

METHODS

A cross-sectional study design was used for this study, and the study was conducted from October 11 to November 30, 2019. A total of 770 prescriptions were selected as per WHO criteria by using systematic random sampling and reviewed with the help of an observational checklist. The data were entered and processed with SPSS version 25 and evaluated using the WHO criteria.

RESULT

The average number of drugs per prescription was 1.8 and 2.05, antibiotics encountered were 77.7% and 72.5%, injections encountered were 5.97% and 7.01%, percentage of drugs prescribed by generic names was 97% and 93.4%, counseling time was 1.6 minutes and 2.25 minutes, and dispensing time was 51.3 seconds and 62.72 seconds at Finoteselam and Asirade Zewudie hospitals, respectively.

CONCLUSION

The majority of WHO core drug use indicators were not met in the two hospitals. The average number of drugs encountered in Asirade Zewudie hospital was slightly higher than the WHO recommended range, whereas the average number of drugs encountered in Finoteselam hospital was exactly equal. The percentage of antibiotics encountered was very high compared with WHO recommendation, but the percentage of injections encountered was below the WHO recommended range and time spent on counseling and dispensing was too short when compared with WHO recommendation. In addition to this, both hospitals had no essential drug list or formulary as well as a key drug list.

摘要

背景

合理用药要求患者使用符合临床需求的药物,剂量符合个体需求,用药时间足够长,在充分知情的情况下,以最低的成本为患者及其所在社区提供药物,且成本尽可能低。如果不能满足其中一项要求,则称之为不合理用药。世界上有许多药物被不当销售或开具处方,世界上相当一部分人口无法获得基本药物。本研究旨在评估芬特斯塞拉姆和阿西拉德泽武迪医院的合理用药实践。

方法

本研究采用横断面研究设计,于 2019 年 10 月 11 日至 11 月 30 日进行。根据世卫组织标准,通过系统随机抽样选择了 770 张处方,并借助观察检查表进行了审查。使用 SPSS 版本 25 输入和处理数据,并根据世卫组织标准进行评估。

结果

每张处方的平均用药数为 1.8 和 2.05,遇到的抗生素分别为 77.7%和 72.5%,遇到的注射剂分别为 5.97%和 7.01%,以通用名开处方的药物比例分别为 97%和 93.4%,咨询时间分别为 1.6 分钟和 2.25 分钟,发药时间分别为 51.3 秒和 62.72 秒,分别在芬特斯塞拉姆和阿西拉德泽武迪医院。

结论

在这两家医院,大多数世卫组织核心药物使用指标都没有得到满足。阿西拉德泽武迪医院遇到的平均药物数量略高于世卫组织推荐范围,而芬特斯塞拉姆医院遇到的平均药物数量正好相等。遇到的抗生素比例非常高,与世卫组织的建议相比,而遇到的注射剂比例低于世卫组织的推荐范围,与世卫组织的建议相比,咨询和发药时间过短。除此之外,这两家医院都没有基本药物清单或处方集以及关键药物清单。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e5d/7474790/893a6e35836d/TSWJ2020-1634294.001.jpg

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