Abebe Gedif Meseret
Wolaita Sodo University, College of Natural and Computational Science, Department of Biology, Wolaita Sodo, Ethiopia.
Int J Microbiol. 2020 Aug 25;2020:1705814. doi: 10.1155/2020/1705814. eCollection 2020.
Biofilm is a microbial association or community attached to different biotic or abiotic surfaces or environments. These surface-attached microbial communities can be found in food, medical, industrial, and natural environments. Biofilm is a critical problem in the medical sector since it is formed on medical implants within human tissue and involved in a multitude of serious chronic infections. Food and food processing surface become an ideal environment for biofilm formation where there are sufficient nutrients for microbial growth and attachment. Therefore, biofilm formation on these surfaces, especially on food processing surface becomes a challenge in food safety and human health. Microorganisms within a biofilm are encased within a matrix of extracellular polymeric substances that can act as a barrier and recalcitrant for different hostile conditions such as sanitizers, antibiotics, and other hygienic conditions. Generally, they persist and exist in food processing environments where they become a source of cross-contamination and foodborne diseases. The other critical issue with biofilm formation is their antibiotic resistance which makes medication difficult, and they use different physical, physiological, and gene-related factors to develop their resistance mechanisms. In order to mitigate their production and develop controlling methods, it is better to understand growth requirements and mechanisms. Therefore, the aim of this review article is to provide an overview of the role of bacterial biofilms in antibiotic resistance and food contamination and emphasizes ways for controlling its production.
生物膜是附着在不同生物或非生物表面或环境上的微生物聚集体或群落。这些附着在表面的微生物群落可在食品、医疗、工业和自然环境中找到。生物膜在医疗领域是一个关键问题，因为它在人体组织内的医疗植入物上形成，并涉及多种严重的慢性感染。食品和食品加工表面成为生物膜形成的理想环境，因为这里有足够的营养物质供微生物生长和附着。因此，这些表面尤其是食品加工表面上生物膜的形成对食品安全和人类健康构成了挑战。生物膜内的微生物被包裹在细胞外聚合物基质中，该基质可作为屏障，抵御消毒剂、抗生素和其他卫生条件等不同的不利条件。一般来说，它们在食品加工环境中持续存在并成为交叉污染和食源性疾病的来源。生物膜形成的另一个关键问题是它们的抗生素耐药性，这使得用药困难，并且它们利用不同的物理、生理和基因相关因素来发展其耐药机制。为了减少它们的产生并开发控制方法，最好了解其生长要求和机制。因此，这篇综述文章的目的是概述细菌生物膜在抗生素耐药性和食品污染中的作用，并强调控制其产生的方法。
