新型冠状病毒肺炎患者的严重急性呼吸综合征冠状病毒2病毒载量，并与其他呼吸道病毒进行比较。
Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses.
作者信息
Jacot Damien, Greub Gilbert, Jaton Katia, Opota Onya
机构信息
Institute of Microbiology, University Hospital Center and University of Lausanne, Switzerland.
Institute of Microbiology, University Hospital Center and University of Lausanne, Switzerland; Infectious Diseases Service, University Hospital of Lausanne, Lausanne, Switzerland.
出版信息
Microbes Infect. 2020 Nov-Dec;22(10):617-621. doi: 10.1016/j.micinf.2020.08.004. Epub 2020 Sep 7.
RT-PCRs to detect SARS-CoV-2 RNA is key to manage the COVID-19 pandemic. We analyzed SARS-CoV-2 viral loads from 22'323 RT-PCR results according to samples types, gender, age, and health units. Viral load did not show any difference across age and appears to be a poor predictor of disease outcome. SARS-CoV-2 viral load showed similar high viral loads than the one observed for RSV and influenza B. The importance of viral load to predict contagiousness and to assess disease progression is discussed.
检测严重急性呼吸综合征冠状病毒2（SARS-CoV-2）RNA的逆转录聚合酶链反应（RT-PCR）是应对2019冠状病毒病（COVID-19）大流行的关键。我们根据样本类型、性别、年龄和卫生单位，分析了22323份RT-PCR结果中的SARS-CoV-2病毒载量。病毒载量在各年龄段之间未显示出任何差异，似乎也不是疾病预后的良好预测指标。SARS-CoV-2病毒载量显示出与呼吸道合胞病毒（RSV）和乙型流感病毒相似的高病毒载量。本文讨论了病毒载量在预测传染性和评估疾病进展方面的重要性。
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