海洋硅藻（Thalassiosira、Skeletonema 和 Chaetoceros）的生物勘探，以获取脂质和其他增值产品。
Bioprospecting of marine diatoms Thalassiosira, Skeletonema and Chaetoceros for lipids and other value-added products.
机构信息
Diatom Research Laboratory, Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh 201313, India.
Algae Biomass and Energy System R&D Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572, Japan.
出版信息
Bioresour Technol. 2020 Dec;318:124073. doi: 10.1016/j.biortech.2020.124073. Epub 2020 Sep 3.
Diatoms are a major storehouse of valuable fucoxanthin and polyunsaturated fatty acids, with enormous nutraceuticals and biofuel potential. Three marine diatom species isolated from the southern coast of India has been screened and their results show that highest biomass concentration and fucoxanthin yield was obtained in Chaetoceros sp. as 0.217 g L and 0.403 mg L respectively. Lipid % as dry cell weight was maximum in Thalassiosira sp. (52%) followed by Skeletonema sp. (44%) and Chaetoceros sp. (22%). However, protein and secondary metabolites content besides the total antioxidant activity was estimated highest in Skeletonema sp. Having strong inhibition zones of 18-20 mm against all the five strains of bacteria also highlights the highest antibacterial prospect in Skeletonema sp. This work manifests the plasticity of diatoms and may provide useful insights for further species-specific selection for large-scale production of eicosapentaenoic acid, docosahexaenoic acid, fucoxanthin and other metabolites with potential health benefits.
硅藻是一种重要的价值颇高的岩藻黄质和多不饱和脂肪酸的储存库，具有巨大的营养保健品和生物燃料潜力。从印度南部海岸分离出的三种海洋硅藻物种进行了筛选，结果表明，最高的生物量浓度和岩藻黄质产量分别在角毛藻属中获得，分别为 0.217 g/L 和 0.403 mg/L。以干细胞重量计，脂质%在塔玛斯氏藻中最高（52%），其次是 skeletonema sp.（44%）和角毛藻属（22%）。然而，除了总抗氧化活性外，蛋白质和次生代谢物含量在 skeletonema sp.中估计最高。对所有 5 株细菌的抑菌圈均为 18-20mm，这也突出了 skeletonema sp. 具有最高的抗菌前景。这项工作证明了硅藻的可塑性，并可能为进一步进行特定物种的选择提供有用的见解，以大规模生产具有潜在健康益处的二十碳五烯酸、二十二碳六烯酸、岩藻黄质和其他代谢物。
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