Division of Gastroenterology and Hepatology, Department of Medicine, 702 Rotary Circle, Suite 225, Indiana University School of Medicine, Indianapolis, IN46202, USA.
Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA.
Public Health Nutr. 2021 Feb;24(3):531-535. doi: 10.1017/S1368980020003298. Epub 2020 Sep 14.
Food intolerances are commonly reported and are predicted to have gastrointestinal health implications. We aimed to quantify the prevalence of food intolerances among US adults and identify culprit foods through a brief web-based survey.
We invited participation in an online cross-sectional survey involving a single questionnaire. Data were summarised using percentages or medians and interquartile range. Participant characteristics by self-reported food intolerance were compared using the Wilcoxon rank sum test and Pearson's χ2 test. Adjusted analyses were performed using multivariable logistic regression.
The survey was internet-based via Amazon's mechanical Turk, a crowdsourcing website for the completion of requester directed tasks.
Adults who were US-based internet users were invited at ages 18-80.
We collected 2133 survey responses (ages 18-79 years). The rate of food intolerance was 24·8 % (95 % CI 23·0, 26·6) in US adults. Younger (P < 0·01), female (P = 0·05) and Asian, African American or multiple race individuals (P < 0·01) predominated. Lactose intolerance was most common. Frequency of a non-lactose food intolerance was 18·1 % (95 % CI 16·5, 19·8). When categorised broadly, grains, fruit, lactose, fish, vegetables, alcohol and nuts were most troublesome for individuals in that order.
Self-reported food intolerance is common in US internet users. The effect of food on gastrointestinal symptoms and avoidant behaviours deserves further attention.
食物不耐受较为常见，并被预测会对胃肠道健康产生影响。我们旨在通过一项简短的网络调查来量化美国成年人食物不耐受的患病率，并确定罪魁祸首食物。
我们邀请参与者参与一项在线横断面调查，其中涉及一份单一问卷。使用百分比或中位数和四分位间距来总结数据。使用 Wilcoxon 秩和检验和 Pearson's χ2 检验比较按自我报告的食物不耐受分类的参与者特征。使用多变量逻辑回归进行调整分析。
该调查通过亚马逊的 Mechanical Turk 进行，这是一个面向完成请求者定向任务的众包网站。
邀请美国的互联网用户（年龄 18-80 岁）参与调查。
我们共收集了 2133 份调查回复（年龄 18-79 岁）。美国成年人的食物不耐受率为 24.8%（95%CI 23.0，26.6）。年轻人（P<0.01）、女性（P=0.05）和亚裔、非裔美国人或多种族人群（P<0.01）居多。乳糖不耐受最为常见。非乳糖食物不耐受的频率为 18.1%（95%CI 16.5，19.8）。当进行广义分类时，谷物、水果、乳糖、鱼类、蔬菜、酒精和坚果依次对个体最具困扰。
自我报告的食物不耐受在美国互联网用户中较为常见。食物对胃肠道症状和回避行为的影响值得进一步关注。
