School of Biomedical Engineering, Western University, London, Ontario, Canada; Imaging Research Laboratories, Robarts Research Institute, Western University, London, Ontario, Canada.
Imaging Research Laboratories, Robarts Research Institute, Western University, London, Ontario, Canada; Department of Electrical and Computer Engineering, Western University, London, Ontario, Canada.
J Arthroplasty. 2021 Feb;36(2):573-578. doi: 10.1016/j.arth.2020.08.034. Epub 2020 Aug 19.
The prevalence of falls affects the wellbeing of aging adults and places an economic burden on the healthcare system. Integration of wearable sensors into existing fall risk assessment tools enables objective data collection that describes the functional ability of patients. In this study, supervised machine learning was applied to sensor-derived metrics to predict the fall risk of patients following total hip arthroplasty.
At preoperative, 2-week, and 6-week postoperative appointments, patients (n = 72) were instrumented with sensors while they performed the timed-up-and-go walking test. Preoperative and 2-week postoperative data were used to form the feature sets and 6-week total times were used as labels. Support vector machine and linear discriminant analysis classifier models were developed and tested on various combinations of feature sets and feature reduction schemes. Using a 10-fold leave-some-subjects-out testing scheme, the accuracy, sensitivity, specificity, and area under the receiver-operator curve (AUC) were evaluated for all models.
A high performance model (accuracy = 0.87, sensitivity = 0.97, specificity = 0.46, AUC = 0.82) was obtained with a support vector machine classifier using sensor-derived metrics from only the preoperative appointment. An overall improved performance (accuracy = 0.90, sensitivity = 0.93, specificity = 0.59, AUC = 0.88) was achieved with a linear discriminant analysis classifier when 2-week postoperative data were added to the preoperative data.
The high accuracy of the fall risk prediction models is valuable for patients, clinicians, and the healthcare system. High-risk patients can implement preventative measures and low-risk patients can be directed to enhanced recovery care programs.
跌倒的发生率影响着老年人的健康,并给医疗保健系统带来经济负担。将可穿戴传感器集成到现有的跌倒风险评估工具中,可以实现对患者功能能力的客观数据采集。本研究应用监督机器学习对传感器衍生指标进行分析,以预测全髋关节置换术后患者的跌倒风险。
在术前、术后 2 周和 6 周的预约中,患者(n=72)佩戴传感器进行计时起立行走测试。术前和术后 2 周的数据用于构建特征集,6 周的总时间用作标签。开发并测试了支持向量机和线性判别分析分类器模型,这些模型结合了各种特征集和特征降维方案。使用 10 折留一交叉验证测试方案,评估了所有模型的准确性、敏感度、特异性和接收者操作特征曲线(AUC)下的面积。
使用支持向量机分类器,仅使用术前就诊时的传感器衍生指标,得到了一个高性能模型(准确性=0.87,敏感度=0.97,特异性=0.46,AUC=0.82)。当将术后 2 周的数据添加到术前数据中时,线性判别分析分类器的整体性能得到了提高(准确性=0.90,敏感度=0.93,特异性=0.59,AUC=0.88)。
跌倒风险预测模型的高准确性对患者、临床医生和医疗保健系统都具有重要价值。高风险患者可以采取预防措施,低风险患者可以接受强化康复护理方案。