Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongup 56212, Korea.
Department of Life-Resources, Graduate School, Sunchon National University, Suncheon 57922, Korea.
Molecules. 2020 Sep 12;25(18):4190. doi: 10.3390/molecules25184190.
Hibiscus species are rich in phenolic compounds and have been traditionally used for improving human health through their bioactive activities. The present study investigated the phenolic compounds of leaf extracts from 18 different accessions and evaluated their biofunctional properties, focusing on antioxidant and antibacterial activity. The most abundant phenolic compound in was caffeic acid, with levels ranging from 14.95 to 42.93 mg/100 g. The antioxidant activity measured by the ABTS assay allowed the accessions to be classified into two groups: a high activity group with red leaf varieties (74.71-84.02%) and a relatively low activity group with green leaf varieties (57.47-65.94%). The antioxidant activity was significantly correlated with TAC (0.933), Dp3-Sam (0.932), Dp3-Glu (0.924), and Cy3-Sam (0.913) contents ( < 0.001). The phenolic extracts exhibited antibacterial activity against two bacteria, with zones of inhibition between 12.00 and 13.67 mm (), and 10.67 and 13.33 mm (). All accessions exhibited a basal antibacterial activity level (12 mm) against the Gram-positive , with PI500758 and PI500764 exhibiting increased antibacterial activity (13.67 mm), but they exhibited a more dynamic antibacterial activity level against the Gram-negative .
芙蓉属植物富含酚类化合物,传统上被用于通过其生物活性来改善人类健康。本研究调查了 18 种不同品种叶片提取物中的酚类化合物,并评估了它们的生物功能特性,重点是抗氧化和抗菌活性。含量最丰富的酚类化合物是咖啡酸,其含量范围为 14.95-42.93mg/100g。ABTS 测定法测定的抗氧化活性使品种分为两组:具有红叶品种的高活性组(74.71-84.02%)和具有绿叶品种的相对低活性组(57.47-65.94%)。抗氧化活性与 TAC(0.933)、Dp3-Sam(0.932)、Dp3-Glu(0.924)和 Cy3-Sam(0.913)含量显著相关(<0.001)。酚类提取物对两种细菌表现出抗菌活性,抑菌圈直径在 12.00-13.67mm()之间,对革兰氏阳性菌的抑菌圈直径在 10.67-13.33mm()之间。所有品种对革兰氏阳性菌均表现出基本的抗菌活性水平(12mm),PI500758 和 PI500764 表现出增强的抗菌活性(13.67mm),但对革兰氏阴性菌表现出更动态的抗菌活性水平。