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脂肪的真相：脂质在新陈代谢、疾病和治疗中的作用的新见解。

Facts about Fats: New Insights into the Role of Lipids in Metabolism, Disease and Therapy.

机构信息

Department of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche (Is), Italy.

Department of Science, University Roma Tre, Viale Marconi 446, 00146 Rome, Italy.

出版信息

Int J Mol Sci. 2020 Sep 11;21(18):6651. doi: 10.3390/ijms21186651.

DOI:10.3390/ijms21186651
PMID:32932833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7554695/
Abstract

Although initially regarded as a passive system to store energy, lipids are now considered to play crucial, structural and functional roles in almost all the biological processes involved in the regulation of physiological and pathological conditions [...].

摘要

尽管最初被认为是一种储存能量的被动系统，但脂质现在被认为在几乎所有参与调节生理和病理状况的生物过程中发挥着关键的结构和功能作用[...]。

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[Role of the concentration of bile acids in the metabolism of lipids. 3. Absorption of fats in man].[胆汁酸浓度在脂质代谢中的作用。3. 人体脂肪的吸收]
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Int J Mol Sci. 2020 Aug 25;21(17):6113. doi: 10.3390/ijms21176113.
2
Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention.脂类与癌症：在发病机制、诊断和治疗干预中的新作用。
Adv Drug Deliv Rev. 2020;159:245-293. doi: 10.1016/j.addr.2020.07.013. Epub 2020 Jul 23.
3
Modulation of DNA Damage Response by Sphingolipid Signaling: An Interplay that Shapes Cell Fate.鞘脂信号对 DNA 损伤反应的调节：决定细胞命运的相互作用。
Int J Mol Sci. 2020 Jun 24;21(12):4481. doi: 10.3390/ijms21124481.
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Lipid Mediators Regulate Pulmonary Fibrosis: Potential Mechanisms and Signaling Pathways.脂质介质调控肺纤维化：潜在机制和信号通路。
Int J Mol Sci. 2020 Jun 15;21(12):4257. doi: 10.3390/ijms21124257.
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The Role of High-Density Lipoproteins in Endothelial Cell Metabolism and Diabetes-Impaired Angiogenesis.高密度脂蛋白在血管内皮细胞代谢和糖尿病受损血管生成中的作用。
Int J Mol Sci. 2020 May 21;21(10):3633. doi: 10.3390/ijms21103633.
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Lipids and Lipid Mediators Associated with the Risk and Pathology of Ischemic Stroke.与缺血性脑卒中风险和病理相关的脂质和脂质介质。
Int J Mol Sci. 2020 May 20;21(10):3618. doi: 10.3390/ijms21103618.
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Acid and Neutral Sphingomyelinase Behavior in Radiation-Induced Liver Pyroptosis and in the Protective/Preventive Role of rMnSOD.酸性和中性鞘磷脂酶在辐射诱导的肝细胞焦亡中的行为及 rMnSOD 的保护/预防作用。
Int J Mol Sci. 2020 May 6;21(9):3281. doi: 10.3390/ijms21093281.
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