• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

少突胶质细胞生理学与病理学功能。

Oligodendrocyte Physiology and Pathology Function.

机构信息

Institute of Anatomy, Rostock University Medical Center, Gertrudenstrasse 9, 18057 Rostock, Germany.

Center for Transdisciplinary Neurosciences Rostock (CTNR), Rostock University Medical Center, Gelsheimer Strasse 20, 18147 Rostock, Germany.

出版信息

Cells. 2020 Sep 11;9(9):2078. doi: 10.3390/cells9092078.

DOI:10.3390/cells9092078
PMID:32932835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7563511/
Abstract

The adult vertebrate central nervous system (CNS) mainly consists of neurons, astrocytes, microglia cells and oligodendrocytes [...].

摘要

成人中枢神经系统（CNS）主要由神经元、星形胶质细胞、小胶质细胞和少突胶质细胞组成。

相似文献

1
Oligodendrocyte Physiology and Pathology Function.少突胶质细胞生理学与病理学功能。
Cells. 2020 Sep 11;9(9):2078. doi: 10.3390/cells9092078.
2
Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System Demyelination.产气荚膜梭菌ε毒素导致成熟少突胶质细胞选择性死亡和中枢神经系统脱髓鞘。
mBio. 2015 Jun 16;6(3):e02513. doi: 10.1128/mBio.02513-14.
3
Contribution of the oligodendrocyte lineage to CNS repair and neurodegenerative pathologies.少突胶质细胞谱系对中枢神经系统修复和神经退行性病变的作用。
Neuropharmacology. 2016 Nov;110(Pt B):539-547. doi: 10.1016/j.neuropharm.2016.04.026. Epub 2016 Apr 21.
4
Oligodendrocyte-derived J1-160/180 extracellular matrix glycoproteins are adhesive or repulsive depending on the partner cell type and time of interaction.少突胶质细胞衍生的J1-160/180细胞外基质糖蛋白具有黏附性或排斥性，这取决于相互作用的细胞类型和时间。
Exp Neurol. 1990 Jul;109(1):98-110. doi: 10.1016/s0014-4886(05)80012-3.
5
The remyelinating potential and in vitro differentiation of MOG-expressing oligodendrocyte precursors isolated from the adult rat CNS.从成年大鼠中枢神经系统分离出的表达髓鞘少突胶质细胞糖蛋白（MOG）的少突胶质前体细胞的髓鞘再生潜力及体外分化
Eur J Neurosci. 2004 Sep;20(6):1445-60. doi: 10.1111/j.1460-9568.2004.03606.x.
6
A Role of Microtubules in Oligodendrocyte Differentiation.微管在少突胶质细胞分化中的作用。
Int J Mol Sci. 2020 Feb 5;21(3):1062. doi: 10.3390/ijms21031062.
7
Central nervous system regenerative failure: role of oligodendrocytes, astrocytes, and microglia.中枢神经系统再生失败：少突胶质细胞、星形胶质细胞和小胶质细胞的作用
Cold Spring Harb Perspect Biol. 2014 Dec 4;7(3):a020602. doi: 10.1101/cshperspect.a020602.
8
Asynchronous differentiation of clonally related spinal cord oligodendrocytes.克隆相关脊髓少突胶质细胞的异步分化
Mol Cell Neurosci. 1995 Feb;6(1):16-31. doi: 10.1006/mcne.1995.1003.
9
Expression of the anaphylatoxin C5a receptor in the oligodendrocyte lineage.过敏毒素C5a受体在少突胶质细胞谱系中的表达。
Brain Res. 2001 Mar 16;894(2):321-6. doi: 10.1016/s0006-8993(01)02003-0.
10
MicroRNA: Key regulators of oligodendrocyte development and pathobiology.微小RNA：少突胶质细胞发育和病理生物学的关键调节因子。
Int J Biochem Cell Biol. 2015 Aug;65:134-8. doi: 10.1016/j.biocel.2015.05.021. Epub 2015 May 27.

引用本文的文献

1
Gut-Brain-Microbiome Axis in the Regulation of Cancer Immune Escape and Immunotherapy in Tumors.肠道-脑-微生物群轴在肿瘤免疫逃逸及免疫治疗调控中的作用
Research (Wash D C). 2025 Sep 11;8:0885. doi: 10.34133/research.0885. eCollection 2025.
2
2-Methoxyestradiol, an Endogenous 17β-Estradiol Metabolite, Induces Antimitogenic and Apoptotic Actions in Oligodendroglial Precursor Cells and Triggers Endoreduplication via the p53 Pathway.2-甲氧基雌二醇，一种内源性 17β-雌二醇代谢物，可诱导少突胶质前体细胞的抗有丝分裂和凋亡作用，并通过 p53 途径触发内复制。
Cells. 2024 Jun 22;13(13):1086. doi: 10.3390/cells13131086.
3
Insulin-like growth factor 1 in heat stress-induced neuroinflammation: novel perspective about the neuroprotective role of chromium.热应激诱导神经炎症中的胰岛素样生长因子1：关于铬神经保护作用的新观点
Stress Biol. 2023 Jul 12;3(1):23. doi: 10.1007/s44154-023-00105-1.
4
Identification of protein-protein interaction bridges for multiple sclerosis.鉴定多发性硬化症的蛋白-蛋白相互作用桥。
Bioinformatics. 2023 Apr 3;39(4). doi: 10.1093/bioinformatics/btad175.
5
Non-genomic Effect of Estradiol on the Neurovascular Unit and Possible Involvement in the Cerebral Vascular Accident.雌二醇对神经血管单元的非基因组效应及其在脑血管意外中的可能作用
Mol Neurobiol. 2023 Apr;60(4):1964-1985. doi: 10.1007/s12035-022-03178-7. Epub 2023 Jan 4.
6
Characterization of gene expression profiles in the mouse brain after 35 days of spaceflight mission.太空飞行任务35天后小鼠大脑中基因表达谱的特征分析。
NPJ Microgravity. 2022 Aug 10;8(1):35. doi: 10.1038/s41526-022-00217-4.
7
Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms.脑细胞类型特异性核蛋白质组学对于解析神经退行性疾病机制至关重要。
Front Neurosci. 2022 Jun 16;16:902146. doi: 10.3389/fnins.2022.902146. eCollection 2022.
8
The Modulatory Effect of Flavonoids on Intestinal Microbiota and Hypothalamus Clock Genes in a Circadian Rhythm Disorder Mouse Model.黄酮类化合物对昼夜节律紊乱模型小鼠肠道微生物群和下丘脑时钟基因的调节作用。
Nutrients. 2022 May 31;14(11):2308. doi: 10.3390/nu14112308.
9
Deficiency of Autism-Related Gene Dock4 Leads to Impaired Spatial Memory and Hippocampal Function in Mice at Late Middle Age.自闭症相关基因Dock4的缺失导致中年后期小鼠空间记忆和海马功能受损。
Cell Mol Neurobiol. 2023 Apr;43(3):1129-1146. doi: 10.1007/s10571-022-01233-4. Epub 2022 May 30.
10
Iron Transporters and Ferroptosis in Malignant Brain Tumors.恶性脑肿瘤中的铁转运蛋白与铁死亡
Front Oncol. 2022 Apr 21;12:861834. doi: 10.3389/fonc.2022.861834. eCollection 2022.

本文引用的文献

1
Oxidative/Nitroxidative Stress and Multiple Sclerosis.氧化/氮氧应激与多发性硬化症。
J Mol Neurosci. 2021 Mar;71(3):506-514. doi: 10.1007/s12031-020-01672-y. Epub 2020 Aug 7.
2
Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone Model.在 Cuprizone 模型中，年老小鼠的脱髓鞘和髓鞘再生受损。
Cells. 2020 Apr 11;9(4):945. doi: 10.3390/cells9040945.
3
Astrocyte and Oligodendrocyte Cross-Talk in the Central Nervous System.星形胶质细胞和少突胶质细胞在中枢神经系统中的相互作用。
Cells. 2020 Mar 3;9(3):600. doi: 10.3390/cells9030600.
4
Investigation of Cuprizone-Induced Demyelination in mGFAP-Driven Conditional Transient Receptor Potential Ankyrin 1 (TRPA1) Receptor Knockout Mice.mGFAP 驱动的条件性瞬时受体电位阳离子通道亚家族 A 成员 1 (TRPA1) 受体敲除小鼠中铜蓝蛋白诱导的脱髓鞘研究。
Cells. 2019 Dec 28;9(1):81. doi: 10.3390/cells9010081.
5
Aberrant Oligodendrogenesis in Down Syndrome: Shift in Gliogenesis?唐氏综合征中的异常少突胶质细胞生成：神经胶质生成的转变？
Cells. 2019 Dec 7;8(12):1591. doi: 10.3390/cells8121591.
6
Conditional Deletion of LRP1 Leads to Progressive Loss of Recombined NG2-Expressing Oligodendrocyte Precursor Cells in a Novel Mouse Model.条件性敲除 LRP1 导致新型小鼠模型中 NG2 表达的少突胶质前体细胞进行性丢失。
Cells. 2019 Nov 30;8(12):1550. doi: 10.3390/cells8121550.
7
Oligodendrocytes as A New Therapeutic Target in Schizophrenia: From Histopathological Findings to Neuron-Oligodendrocyte Interaction.少突胶质细胞作为精神分裂症的新治疗靶点：从组织病理学发现到神经元-少突胶质细胞相互作用。
Cells. 2019 Nov 23;8(12):1496. doi: 10.3390/cells8121496.
8
High Speed Ventral Plane Videography as a Convenient Tool to Quantify Motor Deficits during Pre-Clinical Experimental Autoimmune Encephalomyelitis.高速腹侧平面录像作为一种方便的工具，用于量化临床前实验性自身免疫性脑脊髓炎期间的运动缺陷。
Cells. 2019 Nov 14;8(11):1439. doi: 10.3390/cells8111439.
9
Combinatory Multifactor Treatment Effects on Primary Nanofiber Oligodendrocyte Cultures.组合式多因素对原代少突胶质细胞纤维培养物的作用。
Cells. 2019 Nov 12;8(11):1422. doi: 10.3390/cells8111422.
10
Oligodendrocytes in Development, Myelin Generation and Beyond.少突胶质细胞在发育、髓鞘生成及其他方面的作用。
Cells. 2019 Nov 12;8(11):1424. doi: 10.3390/cells8111424.