Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Department of Dance, University of Illinois at Urbana-Champaign, Urbana, 61801, USA.
Trials. 2020 Sep 15;21(1):792. doi: 10.1186/s13063-020-04723-2.
Cancer survivors experience compromised quality of life due to impaired cognitive function as a result of cancer diagnosis and treatment. Although exercise has proven to be effective in improving cognitive function across the lifespan, interventions comprehensively testing the effectiveness for cancer survivors are limited. The STAY Fit Trial is a three-armed pilot randomized controlled trial designed to compare the effects of a 12-week yoga, aerobic walking, and stretch and tone intervention on cognitive function among adult cancer survivors.
This pilot study aims to recruit 75 adult cancer survivors who will complete assessments of cognitive function, cardiovascular fitness, physical activity, and psychosocial measures at baseline and after the 12-week intervention. The aims of STAY Fit are (1) to assess the efficacy of yoga to improve cognitive function among cancer survivors, compared to aerobic exercise and an active control group; (2) to examine changes in cardiovascular fitness as a result of the interventions; and (3) to assess changes in quality of life among our population as a result of the exercise interventions.
The STAY Fit Trial will test the effectiveness of yoga, aerobic exercise, and stretching and toning exercises in improving cognitive function and fitness among adult cancer survivors. The results of this pilot study will enable us to understand the most effective physical activity modality to improve cognitive function in this population and potentially combat cancer-related cognitive impairment.
ClinicalTrials.gov NCT03650322 . Registered on 28 August 2018.
癌症幸存者由于癌症诊断和治疗导致认知功能受损，生活质量下降。尽管运动已被证明在改善整个生命周期的认知功能方面是有效的，但针对癌症幸存者的综合干预措施有限。STAY Fit 试验是一项三臂试验性随机对照试验，旨在比较 12 周瑜伽、有氧运动和拉伸与调节干预对成年癌症幸存者认知功能的影响。
本研究旨在招募 75 名成年癌症幸存者，他们将在基线和 12 周干预后完成认知功能、心血管健康、身体活动和心理社会测量的评估。STAY Fit 的目的是：（1）评估瑜伽对改善癌症幸存者认知功能的效果，与有氧运动和积极对照组进行比较；（2）研究干预措施对心血管健康的影响；（3）评估运动干预对我们人群生活质量的影响。
STAY Fit 试验将测试瑜伽、有氧运动和拉伸与调节运动在改善成年癌症幸存者认知功能和健康方面的有效性。这项初步研究的结果将使我们能够了解最有效的体育活动模式，以提高这一人群的认知功能，并可能对抗与癌症相关的认知障碍。
ClinicalTrials.gov NCT03650322. 于 2018 年 8 月 28 日注册。
