Poder Thomas G, Wang Liang, Carrier Nathalie
School of Public Health, University of Montreal, Montreal, Québec, Canada
Centre de recherche de l'IUSMM, CIUSSS de l'Est de l'île de Montréal, Montréal, Québec, Canada.
BMJ Open. 2020 Sep 15;10(9):e035722. doi: 10.1136/bmjopen-2019-035722.
To describe how chronic low back pain (CLBP) impacts on utility scores and which patients' characteristics most affect these scores in the province of Quebec.
Province of Quebec, Canada.
569 adult patients with CLBP.
An online survey on low back pain was conducted between October 2018 and January 2019. The EuroQol Five Dimensions (EQ-5D-5L) and the Short Form Six Dimensions version 2 (SF-6Dv2) are two generic preference-based measures used to evaluate health-related quality of life (HRQoL) and provide quality-adjusted life-year utility values.
The number of subjects who agreed to participate was 610, but 41 were excluded because 8 had low back pain for less than 3 months and 33 did not start the survey. A total of 569 subjects were analysed, but only 410 completed the survey up to the EQ-5D-5L or SF-6Dv2 sections. Median (range) of EQ-5D-5L was 0.622 (-0.072 to 0.905), and mean (range) of SF-6Dv2 and EQ-Visual Analogue Scale was 0.561 (0.301-0.829) and 51.0 (0-100), respectively. In all multivariate models, health or life satisfaction increased the health utility score, while pain reduced it. Co-occurring health problems were present for a majority (68%) of participants, mainly fatigue/insomnia (57.4%), musculoskeletal disorder (56.2%) and mental disorder (44%).
This study provided utility scores with EQ-5D-5L and SF-6Dv2 in patients with CLBP in Quebec, and results were similar to other studies conducted in different settings. These values were well below those reported in the Quebec general population and highlight the association between CLBP and HRQoL.
描述慢性下腰痛（CLBP）如何影响效用评分，以及在魁北克省哪些患者特征对这些评分影响最大。
加拿大魁北克省。
569名成年CLBP患者。
2018年10月至2019年1月进行了一项关于下腰痛的在线调查。欧洲五维健康量表（EQ-5D-5L）和简式六维量表第2版（SF-6Dv2）是两种基于偏好的通用测量方法，用于评估健康相关生活质量（HRQoL）并提供质量调整生命年效用值。
同意参与的受试者有610名，但41名被排除，原因是8名下腰痛时间少于3个月，33名未开始调查。共分析了569名受试者，但只有410名完成了直至EQ-5D-5L或SF-6Dv2部分的调查。EQ-5D-5L的中位数（范围）为0.622（-0.072至0.905），SF-6Dv2和EQ视觉模拟量表的均值（范围）分别为0.561（0.301 - 0.829）和51.0（0 - 100）。在所有多变量模型中，健康或生活满意度提高了健康效用评分，而疼痛则降低了该评分。大多数（68%）参与者存在并发健康问题，主要是疲劳/失眠（57.4%）、肌肉骨骼疾病（56.2%）和精神障碍（44%）。
本研究提供了魁北克CLBP患者的EQ-5D-5L和SF-6Dv2效用评分，结果与在不同环境中进行的其他研究相似。这些值远低于魁北克普通人群报告的值，并突出了CLBP与HRQoL之间的关联。
