Department of Human Nutrition, University of Otago, Dunedin, New Zealand.
Department of Psychology, University of Otago, Dunedin, New Zealand.
Eur J Clin Nutr. 2021 Apr;75(4):602-610. doi: 10.1038/s41430-020-00749-6. Epub 2020 Sep 17.
BACKGROUND/OBJECTIVE: The relationship between postprandial glycaemic responses and cognitive performance, mood and satiety are inconsistent. The objective of this study is to compare the effects of different glycaemic responses, induced by beverages with different glycaemic index (GI) (sucrose and isomaltulose), and a non-glycaemic control (sucralose), on cognition, mood and satiety.
SUBJECTS/METHODS: In this double-blinded, randomised crossover trial, healthy adults (n = 55) received sucrose (GI 65), isomaltulose (GI 32) and sucralose (non-caloric negative control) drinks on separate occasions. The Complex Figure test, the Word Recall test, Trail Making Test Part B and the Stroop test were administered 60 min after beverages ingestion. Mood and satiety were tested along with cognitive performance.
Comparing between isomaltulose and sucrose, there were no significant differences in the mean (95% CI) for the following: Complex Figure: immediate recall -0.6 (-1.7, 0.5), delayed recall -0.8 (-1.9, 0.3); Word recall: immediate recall 0.2 (-0.7, 1.1), delayed recall 0.5 (-0.4, 1.4); Trail Making: completing time -2.4 (-7.5, 2.7) s; Stroop: time used for correct congruent responses -9 (-31, 14) ms and correct incongruent responses -18 (-42, 6) ms. No differences among beverages were found in the mood and satiety scores with exception that participants felt more energetic 60 min after isomaltulose ingestion (p = 0.028 for difference with sucrose) and hungrier 30 min after isomaltulose ingestion (p = 0.036 for difference with sucrose; p = 0.022 for difference with sucralose).
Under these study conditions there is no convincing evidence for an effect of glycaemic response on cognitive performance, mood or satiety.
背景/目的：进食后血糖反应与认知表现、情绪和饱腹感之间的关系并不一致。本研究旨在比较不同血糖反应（由不同血糖指数（GI）的饮料引起，即蔗糖和异麦芽酮糖，以及非血糖控制（三氯蔗糖））对认知、情绪和饱腹感的影响。
受试者/方法：在这项双盲、随机交叉试验中，健康成年人（n=55）分别接受蔗糖（GI 65）、异麦芽酮糖（GI 32）和三氯蔗糖（无热量负对照）饮料。在饮料摄入 60 分钟后进行复杂图形测试、单词回忆测试、追踪测试 B 和斯特鲁普测试。同时测试情绪和饱腹感以及认知表现。
与蔗糖相比，异麦芽酮糖和蔗糖之间的平均（95%CI）差异无统计学意义：复杂图形：即刻回忆-0.6（-1.7，0.5），延迟回忆-0.8（-1.9，0.3）；单词回忆：即刻回忆 0.2（-0.7，1.1），延迟回忆 0.5（-0.4，1.4）；追踪：完成时间-2.4（-7.5，2.7）秒；斯特鲁普：正确一致反应用时-9（-31，14）毫秒和正确不一致反应用时-18（-42，6）毫秒。除了异麦芽酮糖摄入后 60 分钟参与者感觉更有活力（与蔗糖差异，p=0.028）和异麦芽酮糖摄入后 30 分钟饥饿感更强（与蔗糖差异，p=0.036；与三氯蔗糖差异，p=0.022）外，三种饮料在情绪和饱腹感评分方面没有差异。
在这些研究条件下，没有令人信服的证据表明血糖反应对认知表现、情绪或饱腹感有影响。
