抗病毒漱口水：基于循证方法对新冠病毒病可能具有的益处。
Antiviral mouthwashes: possible benefit for COVID-19 with evidence-based approach.
作者信息
Moosavi Mahdieh-Sadat, Aminishakib Pouyan, Ansari Maryam
机构信息
Dental Research Center, Dentistry Research Institute, Department of Oral Medicine, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Oral and Maxillofacial Pathology Department, Pathology Department, School of Dentistry, Cancer Institute Hospital, IKHC, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
J Oral Microbiol. 2020 Jul 17;12(1):1794363. doi: 10.1080/20002297.2020.1794363.
BACKGROUND
The outbreak, and pandemic of COVID-19 causing widespread concerns in all health systems of countries. Virus-carrying aerosols can penetrate the healthy human body and lungs, resulting in rapid transmission. For the first time, in this evidence-based article, the effects of different types of mouthwashes to reduce the viral load were investigated. Also, another aim of this essay is a reduction in viral load in patients with COVID-19 and prevention developing ventilator-associated pneumonia in critically ill patients.
METHODS
Related databases were comprehensively searched for relevant studies. The present study was performed according to the preferred cases for standard systematic reviews (PRISMA).
RESULTS
Five original studies in which the subject matter was directly evaluated were included. Different types of mouthwashes and viruses were investigated in this study.
CONCLUSIONS
The antiviral mouthwashes play a certainly important role in reducing the viral load of the salivary virus. In the present study, this importance could be proved in two different aspects, that is, the use of mouthwash before dental procedures to reduce the risk of transmission of the virus to the dental team and the use of this mouthwash in COVID-19 patients to help improve systemic problems associated with oral microbial flora.
背景
新型冠状病毒肺炎（COVID-19）的爆发和大流行引起了各国所有卫生系统的广泛关注。携带病毒的气溶胶可侵入健康人体和肺部，导致快速传播。在这篇循证文章中，首次研究了不同类型漱口水对降低病毒载量的效果。此外，本文的另一个目的是降低COVID-19患者的病毒载量，并预防重症患者发生呼吸机相关性肺炎。
方法
全面检索相关数据库以查找相关研究。本研究按照标准系统评价的首选报告项目（PRISMA）进行。
结果
纳入了五项直接评估主题事项的原始研究。本研究调查了不同类型的漱口水和病毒。
结论
抗病毒漱口水在降低唾液病毒载量方面确实发挥着重要作用。在本研究中，这一重要性可从两个不同方面得到证明，即在牙科手术前使用漱口水以降低病毒传播给牙科团队的风险，以及在COVID-19患者中使用这种漱口水以帮助改善与口腔微生物群相关的全身问题。
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