State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Int J Oral Sci. 2020 Mar 3;12(1):9. doi: 10.1038/s41368-020-0075-9.
A novel β-coronavirus (2019-nCoV) caused severe and even fetal pneumonia explored in a seafood market of Wuhan city, Hubei province, China, and rapidly spread to other provinces of China and other countries. The 2019-nCoV was different from SARS-CoV, but shared the same host receptor the human angiotensin-converting enzyme 2 (ACE2). The natural host of 2019-nCoV may be the bat Rhinolophus affinis as 2019-nCoV showed 96.2% of whole-genome identity to BatCoV RaTG13. The person-to-person transmission routes of 2019-nCoV included direct transmission, such as cough, sneeze, droplet inhalation transmission, and contact transmission, such as the contact with oral, nasal, and eye mucous membranes. 2019-nCoV can also be transmitted through the saliva, and the fetal-oral routes may also be a potential person-to-person transmission route. The participants in dental practice expose to tremendous risk of 2019-nCoV infection due to the face-to-face communication and the exposure to saliva, blood, and other body fluids, and the handling of sharp instruments. Dental professionals play great roles in preventing the transmission of 2019-nCoV. Here we recommend the infection control measures during dental practice to block the person-to-person transmission routes in dental clinics and hospitals.
一种新型 β 冠状病毒（2019-nCoV）引起了严重的肺炎，甚至是胎儿肺炎，该病毒最初在中国湖北省武汉市的一个海鲜市场被发现，并迅速传播到中国其他省份和其他国家。2019-nCoV 与 SARS-CoV 不同，但共享相同的宿主受体——人血管紧张素转换酶 2（ACE2）。2019-nCoV 的自然宿主可能是蝙蝠 Rhinolophus affinis，因为 2019-nCoV 与 BatCoV RaTG13 的全基因组同一性为 96.2%。2019-nCoV 的人际传播途径包括直接传播，如咳嗽、打喷嚏、飞沫吸入传播，以及接触传播，如接触口腔、鼻腔和眼部黏膜。2019-nCoV 也可以通过唾液传播，胎儿口腔途径也可能是一种潜在的人际传播途径。由于面对面交流和接触唾液、血液和其他体液以及处理尖锐器械，牙科从业者在牙科实践中面临着巨大的 2019-nCoV 感染风险。牙科专业人员在预防 2019-nCoV 传播方面发挥着重要作用。在这里，我们建议在牙科实践中采取感染控制措施，以阻断牙科诊所和医院中的人际传播途径。
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