Department of General Surgery, University Hospital Hairmyres, East Kilbride, UK.
Department of Medicine, University Hospital Hairmyres, East Kilbride, UK.
J Hosp Infect. 2021 Jan;107:91-94. doi: 10.1016/j.jhin.2020.09.017. Epub 2020 Sep 17.
This study aimed to determine whether nosocomial coronavirus disease 2019 (COVID-19) has a worse outcome compared with community-acquired COVID-19. This was a prospective cohort study of all hospitalized patients with confirmed COVID-19 in three acute hospitals on 9 April 2020. Patients were followed-up for at least 30 days. Nosocomial infection was defined as a positive swab after 7 days of admission. In total, one hundred and seventy-three patients were identified, and 19 (11.0%) had nosocomial infection. Thirty-two (18.5%) patients died within 30 days (all cause) of a positive swab test; there were no significant differences in 30-day all-cause mortality rates between the three groups (i.e. patients admitted with suspected COVID-19, patients with incidental COVID-19 and patients with nosocomial COVID-19): 21.1% vs 17.6% vs 21.6% (P=0.755). Nosocomial COVID-19 is not associated with increased mortality compared with community-acquired COVID-19.
本研究旨在确定医院获得性 2019 年冠状病毒病（COVID-19）与社区获得性 COVID-19 相比是否预后更差。这是一项针对 2020 年 4 月 9 日三家急性医院所有确诊 COVID-19 住院患者的前瞻性队列研究。对至少随访 30 天的患者进行了随访。医院感染的定义为入院后 7 天出现阳性拭子。总共确定了 173 名患者，其中 19 名（11.0%）发生医院感染。32 名（18.5%）患者在阳性拭子检测后 30 天内（全因）死亡；三组 30 天全因死亡率无显著差异（即疑似 COVID-19 入院患者、偶然 COVID-19 患者和医院获得性 COVID-19 患者）：21.1%比 17.6%比 21.6%（P=0.755）。与社区获得性 COVID-19 相比，医院获得性 COVID-19 并不与死亡率增加相关。
