Nobuto T, Tokioka T, Imai H, Suwa F, Ohta Y, Yamaoka A
J Periodontol. 1987 Apr;58(4):240-6. doi: 10.1902/jop.1987.58.4.240.
The healing process in a wound induced by removal of 6 X 6 mm of gingiva and periosteum from the maxillary attached gingiva of 48 adult mongrel dogs was observed to investigate the potential blood supply for grafts placed on denuded bone. Three-dimensional observations were performed over 12 weeks by scanning electron microscopy (SEM) following the manufacture of corrosion capillary casts by acrylic resin injection. Revascularization in the gingival wound was mainly through formation of new capillaries from those existing below the surrounding epithelium with little new capillary formation from the Volkmann canals. Moreover, the periodontium contributed greatly to the vascularization, which was fastest from the gingival margin. Further, simplification of new capillary loops was also fastest from this direction. Regeneration of the periosteum and periosteal vascular plexus was slow, taking about twice the time of connective tissue and capillaries below the epithelium. The results indicated that blood supply to grafts on denuded bone in the early postgraft period would mainly be provided by capillaries below the epithelium surrounding the recipient bed.
为了研究放置在裸露骨上的移植物的潜在血液供应情况，对48只成年杂种犬上颌附着龈切除6×6mm牙龈和骨膜所造成的伤口愈合过程进行了观察。通过丙烯酸树脂注射制作腐蚀毛细血管铸型后，在12周内利用扫描电子显微镜（SEM）进行三维观察。牙龈伤口的血管再生主要是通过周围上皮下方现有的毛细血管形成新的毛细血管，而从Volkmann管形成的新毛细血管很少。此外，牙周膜对血管化有很大贡献，从牙龈边缘开始血管化最快。此外，新毛细血管袢的简化也是从这个方向最快。骨膜和骨膜血管丛的再生缓慢，所需时间约为上皮下方结缔组织和毛细血管的两倍。结果表明，移植后早期裸露骨上移植物的血液供应主要由受植床周围上皮下方的毛细血管提供。
